Arterial blood pressures in 18 lambs who had been nephrectomized 3–24 days before were not significantly different from those of 26 control fetuses or from those of control fetuses in the literature. Plasma renin activities were below the detection level of our assay. The nephrectomized fetuses continued to grow according to a variety of indices. We concluded that neither the kidney nor the renin angiotensin system are necessary for the long-term regulation of fetal blood pressure, probably because of their inability to affect placental exchange of water and electrolytes.
A63-year-old man presented to the ophthalmology department with a 24-hour history of loss of vision in the right eye and 3 days of severe frontal headache. Six weeks earlier a supero-temporal field defect was observed in the left eye during examination by his optician. A routine referral to the ophthalmology department for assessment of possible glaucoma was made. On examination he was alert and orientated. The visual acuity was hand movements in the right eye and 6/12 in the left eye with a dense right relative afferent pupillary defect. Visual fields tested by confrontation demonstrated a bitemporal loss. This was confirmed by formal Goldmann visual fields (Figure 1). There was no papilloedema or external ophthalmoplegia and further ophthalmic examination was unremarkable. There were no focal neurological signs and his blood pressure was normal. Serum prolactin was 400U/litre (normal range: 100–500 mU/litre). A computerized tomography scan (Figure 2) revealed an intrasellar mass expanding the sella turcica and extending into the suprasellar cistern. There were small high density foci suggesting a recent haemorrhage within a pituitary adenoma. The patient underwent transphenoidal decompression of the pituitary tumour and histopathology confirmed haemorrhagic pituitary adenoma. Repeat visual fields within 1 week of surgery (Figure 3) illustrate dramatic recovery of visual function. Two weeks postoperatively, the patient's visual acuity had improved to 6/24 in the right eye and 6/9 in the left with continued improvement in the visual field. After 5 months his visual acuity was 6/18 right and 6/6 left with almost complete recovery of his visual fields and he was able to return to driving.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.