Objective
PerClot® is a biocompatible, polysaccharide haemostatic system recommended for surgical procedures. It is an absorbable modified polymer that is non-pyrogenic and is derived from purified plant starch. Our goal was to evaluate the safety, efficacy and usefulness of PerClot® in head and neck surgery (H&N) in our department.
Methods
All patients who received PerClot® after their neck operation over 1-year period (2019–2020) were prospectively investigated. The information collected included demographics, admission and discharge dates, type of operation, operative details, postoperative complications and their management. The data were collected and analysed using Excel.
Results
A total of 57 patients (males = 26, females = 31) with mean age of 51 (range 19–83) were identified. None of the patients developed primary or secondary haemorrhage. Ten patients suffered from post-operative wound complications (18%). Wound infection was noticed in 9/57 (16%) of patients. 1/57 patients had seroma.
Conclusions
PerClot® is safe, effective in reducing the postoperative bleeding and would appear to be useful in head and neck surgery with minimal adverse effects.
Allergic rhinitis (AR) is a common inflammatory condition of the nasal mucosa affecting approximately 1 in 5 people worldwide. 1 It is characterised by a type I hypersensitivity response, in which repeated allergen exposure results in histamine release by means of mast cell degranulation. 1 In Europe, grass pollen is the most common causative allergen in association with AR. 2 Classic symptoms of AR include sneezing, nasal congestion, nasal and oral pruritus and rhinorrhoea. Associated conditions, like conjunctivitis, asthma and eczema, may contribute towards its diagnosis. 3 Symptom severity varies from mild to severe, with nasal congestion having the largest impact on quality of life. 3 The diagnosis of AR is clinical, based on symptoms, family history of atopy and exclusion of alternative diagnoses, such as infective rhinitis or non-allergic rhinitis. 4 The classification of AR was revised in
We present a rare case of a 23-year-old man with an isolated trochlear fracture following an injury to the left elbow. To our knowledge, there are only a few cases previously reported in the literature. The relevant literature is reviewed.
Background
This study aims to investigate radiological and clinical factors which predict malignancy in indeterminate pulmonary nodules in patients with head and neck cancer (HNC).
Methods
Prospective data were collected in 424 patients who were reviewed in the NHS Lothian HNC multidisciplinary meeting from May 2016 to May 2018. Staging and follow‐up CT chest imaging were reviewed to identify and assess pulmonary nodules in all patients.
Results
About 61.8% of patients had at least one pulmonary nodule at staging CT. In total, 25 patients developed malignancy in the chest. Metastatic disease in the chest was significantly associated with unknown or negative p16 status (p < .0005). Pleural indentation and spiculation were associated with indeterminate nodules, subsequently being shown to represent metastatic disease (p > .0005 and p = .046, respectively).
Conclusion
Negative or unknown p16 status was associated with an increased propensity to develop metastatic disease in the chest in patients with HNC.
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