Introdução: O diagnóstico precoce do risco nutricional pode melhorar o prognóstico dos pacientes onco-hematológicos. Objetivo: Descrever o estado nutricional nos pacientes onco-hematológicos e avaliar os fatores associados ao risco nutricional nos pacientes onco-hematológicos de um hospital universitário terciário de Fortaleza - Ceará. Método: Estudo transversal que incluiu 127 pacientes adultos internados. Os dados de diagnóstico clínico e demográficos foram coletados por meio da análise de prontuários. O estado nutricional foi avaliado pelo índice de massa corporal (IMC), circunferência braquial (CB) e pela aplicação da ferramenta de triagem de risco nutricional - NRS-2002. Resultados: Pelos diferentes parâmetros, houve divergências no estado nutricional. A maioria da amostra apresentava risco nutricional de acordo com a avaliação da NRS-2002 (70,1%; n=89), seguida pela CB (33,9%; n=43) e pelo IMC (8,7%; n=11). Houve correlação positiva significativa entre IMC e idade [r=0,313, p<0,001] e CB [r=0,846, p<0,001] e associação significativa entre NRS-2002≥3 e IMC<18,5 kg/m² (p=0,023); NRS-2002 ≥3 e CB classificada como desnutrição (p=0,001); IMC<18,5kg/m² e CB classificada como desnutrição; e residir em zona urbana e apresentar CB adequado (p=0,023). Conclusão: Este estudo revelou alta prevalência de risco nutricional, bem como uma associação significativa entre risco nutricional e baixos valores de IMC e CB, e residir em zona rural. Assim, há a necessidade de utilizar uma combinação de indicadores, a fim de diagnosticar, de forma mais precisa e precoce, o estado nutricional desses pacientes.
ObjectiveTo analyze the prevalence of overweight and the use of conicity index for cardiovascular risk assessment in individuals submitted to autologous hematopoietic stem cell transplantation.MethodsThe sample comprised 91 patients of both sexes, who underwent autologous hematopoietic stem cell transplantation from September 2008 to December 2013, aged 18 years or over. To determine the nutritional profile, we collected anthropometric data on weight, height, waist circumference upon hospital admission. The body mass index and the conicity index were calculated.ResultsA total of 91 patients diagnosed with multiple myeloma, Hodgkin's lymphoma, non-Hodgkin's lymphoma and other conditions were evaluated. The mean age was 43.5 (14.2) years, 63.7% were male. We verified that according to the body mass index, 63.7% were overweight and, according to waist circumference, 74.7% had a higher risk for cardiovascular diseases. According to the calculation of the conicity index, 92.3% of patients presented increased cardiovascular risk. Patients with multiple myeloma had a higher conicity index when compared to other patients (p<0.01).ConclusionThis study revealed a high prevalence of overweight and cardiovascular risk. It should be noted that the conicity index was a good method to evaluate cardiovascular risk and that new studies using this index should be performed.
Introduction Patients undergoing haemodialysis are at great cardiovascular risk. Neck circumference (NC) is a simple and low‐cost measure for estimating this risk precociously. The present study aimed to evaluate whether the cardiovascular risk obtained by NC is associated with the main cardiometabolic risk factors in patients on haemodialysis treatment who are on a waiting list for transplantation. Methods A cross‐sectional study was conducted including 96 patients in a single transplantation centre. Socio‐demographic, clinical‐laboratory and anthropometric data were collected. NC was considered as a dependent variable and the independent variables were body mass index (BMI), fasting glycaemia and lipid profile, triglyceride and high‐density lipoprotein‐cholesterol (TGL/HDL‐C) ratio, and triglyceride and glycaemia (TyG) index. For the comparison of averages, we used Mann–Whitney and Student’s t tests, as well as one‐way analysis of variance and Kruskal–Wallis tests. Bivariate and multivariate logistic regression was performed for the association between NC and cardiometabolic risk factors. p < 0.05 was considered statistically significant. Results There were higher BMI averages, blood glucose, triglycerides (TGL), TGL/HDL‐C ratio and TyG index in the tertile 3 of the NC, whereas the HDL‐C decreased as the tertile increased. There was a statistically significant risk of cardiovascular disease that was asscoiated, according to NC, with being overweight, high levels of TGL, TGL/HDL‐C, TyG index and low HDL‐C. Conclusions NC is shown to be associated with cardiometabolic risk factors in kidney patients undergoing haemodialysis who are on a transplant waiting list.
Food consumption changed after transplantation. There was no change in the nutritional status from pre- to post-transplant but, in general, most patients had altered nutritional status in both evaluation moments.
O estado nutricional prévio dos indivíduos com doença renal crônica terminal possui importante impacto nos desfechos do Transplante Renal. Com isso, o estudo objetivou caracterizar fatores pertinentes ao estado nutricional em pacientes pré transplante renal de um hospital referência de Fortaleza-CE. Caracteriza-se como estudo transversal, descritivo e retrospectivo constituído por 136 pacientes com idade superior a 18 anos de ambos os sexos admitidos para realizar Transplante Renal no período de março de 2018 a março de 2020. Foram coletados e analisados dados clínicos, bioquímicos e antropométricos. As análises estatísticas foram realizadas utilizando o software Statistical Product and Service Solutions - SPSS® (versão 20). Os dados foram analisados pelos testes exato de Fisher, qui-quadrado (χ2), Kolmogorov-Smirnov, t de Student, Mann-Whitney. Foi considerado nível de significância fixado em p < 0,05. Houve associação significativa entre idade e índice de massa corpórea (IMC). Verificou-se que idosos (≥ 60 anos) tiveram maior razão de chance de apresentarem IMC <18,5 kg/m² (p<0,031). De acordo com os dados bioquímicos, maior parte da amostra, apresenta comprometimento nutricional de acordo com contagem total de linfócitos (CTL) e relação linfócito/monócito. Verificou-se que pacientes com idade ≥60 anos apresentaram menor média de relação linfócito/monócito quando comparados aos pacientes com idade <60 anos. Quanto às comorbidades avaliadas, a hipertensão arterial sistêmica (HAS) foi a mais prevalente na amostra. Idosos mostraram-se mais susceptíveis ao quadro de comprometimento nutricional. Diante de diversos fatores que contribuem para esse quadro é de grande importância a avaliação e o acompanhamento clínico e nutricional desses pacientes.
Objective: The objective of the study was to estimate and analyze the Potential Renal Acid Load (PRAL) of the diet in patients maintenance hemodialysis who are candidates for transplantation. Methodology: A cross-sectional study was conducted. The sample was separated in terciles of the PRAL. For the association between the PRAL and the independent variables, non-adjusted multinomial logistic regression and adjusted by potential confounders were implemented. It was assumed a p< 0,05 for statistical significance. Results: It was noticed that protein (g), the protein /kg of weight (g/kg), % of animal and vegetal protein, the phosphorus (mg), the lipid (g), and the carbohydrate (g) showed differences between the terciles (p<0,05). In regression, the greatest consumption of protein (g), protein g/kg of weight (g/kg), % of animal protein and lipid (g) was associated with the tercile 3 to tercile 1, whereas the greatest consumption of carbohydrate and % vegetal protein showed a protective effect. Conclusion: The results show an association between the PRAL and the protein consumption with the difference between the sources. It was not found an association between PRAL and the variables of nutritional status.
Objective: To evaluate the selenium status and oxidative stress in male infertility cases selected from a private human reproduction center in the state of Ceará, Brazil. Methods: The present study had a cross-sectional quantitative approach, carried out between January and October 2013 at a Human Reproduction Center. The studied population was composed of 49 male individuals seen at the clinic, aged between 18 and 60 years. Blood samples were collected to measure serum selenium concentrations, erythrocyte activity and glutathione peroxidase. After medical diagnosis, the participants were divided into fertile and infertile groups. Blood samples were collected for establishing Se concentrations in plasma and erythrocytes, and measurements of the enzymatic activity of glutathione peroxidase in the erythrocytes. Result: it resulted in 53.1% of fertile men and 46.9% of infertile men. The average age of the fertile group was 34.1 years and the infertile group was 37.3 years. Regarding the assessment of nutritional status, the scatter diagram of the infertility group showed a higher body mass index and waist circumference, showing that this group has a higher risk of global and abdominal obesity compared to the fertile group ( p <0.0001, respectively). There were similarities between the groups regarding caloric intake, macronutrient and selenium intake. Conclusion: We can conclude that the serum values of selenium, in excess and in deficiency, can be harmful to male fertility.
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