Objective: The present research performed a clinical and histopathological analysis of female genital schistosomiasis (FGS) cases. This was a descriptive and retrospective study, with a quantitative approach based on secondary databases belonging to Memorial Nestor Piva from Universidade Tiradentes. Methodology: Medical records and biopsies from patients affected with genital schistosomiasis (1984-1994) 75 pathology reports were found, biopsies of feminine genitals, with the respective paraffin blocks and slides. In these three search blocks, to contain sufficient quantity of biological material underwent histological new. For pathological analysis, hematoxylin-eosin, picrosirius Red and Masson's trichrome staining were used. A distribution of cases per year was performed to obtain an average and a percentage distribution among the most affected organs. In addition, the chi-square test was used to establish an association between schistosomiasis and its anatomical location and with other pathologies. Results: An average of four cases per year was obtained and the infection was found in all genital system organs, with its highest concentration in the ovaries followed by the uterus. In addition, there was an association between the parasitosis and cervical metaplasia, uterine tumors and salpingitis. In the histopathological analysis, several granulomas containing Schistosoma mansoni eggs, in productive and curing phases, were observed. Conclusion: It was concluded that ovaries were the most affected anatomical sites and that the presence of genital schistosomiasis may favor the occurrence of associated pathologies, thus causing a high morbidity rate to women's health.
This study aimed to analyze the performance of the Schistosomiasis Epidemiological Surveillance System in Sergipe, Brazil. This study used a mixed methodology, with a quantitative approach and the application of semi-structured interviews, directed to professionals of Health Surveillance and Primary Care in seven regional health departments headquarters in Sergipe, as well as information obtained in Sistema de Informação do Programa de Controle da Esquistossomose (SISPCE), Sistema de Informação sobre Mortalidade (SIM) and Sistema de Informação de Agravos de Notificação (SINAN). Interviews were applied from March to October 2018 and secondary data obtained in the information systems corresponded to the period between 2013 and 2018, when structure and process indicators were compared with result indicators. The main critical point was the lack of implementation of the Schistosomiasis Control Program (PCE) in the entire endemic area, lack of interaction between Epidemiological Surveillance and Primary Care, deficiencies in the management and execution of field actions. Failures in the implantation in the PCE, in the structure and process of the Surveillance System, in addition to the need for greater integration between the professionals of the Epidemiological Surveillance and other health sectors, negatively influence the results of the PCE, and may have similar causes and results in the others endemics of the state.
Variações anatômicas das artérias coronárias em humanos têm apresentado grande interesse clínico por resultar em melhor entendimento dos processos patológicos cardíacos. Este estudo objetivou analisar a morfometria das artérias coronárias de cadáveres humanos do quarto ao nono mês de vida intrauterina. Um total de 62 corações de fetos brasileiros fixados em formalina, com idades gestacionais de 16 a 36 semanas, distribuídos igualmente quanto ao gênero e a idade fetal em cada grupo, foram analisados. O procedimento de dissecação foi realizado por retirada do coração com os pulmões em monoblocos. O comprimento das artérias em estudo foi mensurado através de fita flexível disposta ao longo dos vasos e posteriormente medida com paquímetro. Além disso, procedeu-se com análise histológica dos tecidos das artérias coronárias para quantificação das fibras elásticas. Os dados foram analisados através da Análise de Variância de dois fatores (Two way-ANOVA), seguido pelo post hoc de Student-Newman-Keuls, considerando p < 0.05. Quando comparado o comprimento da artéria coronária direita (ACD) em fetos entre o segundo e o terceiro trimestre foi encontrada diferença estatisticamente significativa tanto para o gênero masculino (p = 0.04) quanto feminino (p = 0.04). Não se encontrou diferença estatisticamente significativa ao se comparar o comprimento da artéria coronária esquerda (ACE) entre segundo e terceiro trimestre em fetos masculinos (p = 0.07) e femininos (p = 0.09). Percebeu-se a existência de padrão de crescimento semelhante entre fetos masculinos e femininos e desenvolvimento precoce da ACE em relação à ACD.
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