Objective: to assess the prevalence of residual disease in hysterectomy specimens after conization in women treated for squamous microinvasive carcinoma of the uterine cervix (MIC). A cohort of 607 patients with MIC diagnosed and treated at Campinas State University, Brazil was analyzed. All patients underwent cervical conization and of these, 388 followed by hysterectomy. Residual carcinoma / CIS in the hysterectomy was highly associated with positive endocervical conization margins (p<0,0001), in 171 cases of free conization endocervical margins, 32/171 (18.7%) had residual disease: 20 CIS (11.7%), and 12 MIC (7%).Positive endocervical margins are highly associated with residual disease in hysterectomy specimen (61.1%) so further treatment is mandatory. Conservative treatment should be carefully evaluated.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.