Objectives: To determine frequency of histopathological diagnosis in women who underwent hysterectomy for benign condition in tertiary care hospital. Study Design: Retrospective study. Setting: Department of Gynecology and Obstetrics, CMH Nowshera. Period: 6 months (July 2018 December 2019). Material & Methods: Data of all hysterectomies underwent in last 3 years was reviewed. Ethical approval was taken from ethical review board. Patients undergone hysterectomy with benign condition were included in study. Data was analyzed using SPSS version 24. Chi-square and correlation test was performed. P value ≤0.05 was considered significant. Results: Total 430 cases were included in study. Mean age of women was 37.1 years± 8.2 SD. Most common complaints was irregular bleeding 123(28.6%) following dysmenorrhea 78(18.1%). Most common histopathological finding was adenomyosis 214(49.8%), following leiomyoma 66(15.3%). Histopathological findings were significantly associated parity (p=0.000), type of hysterectomy (p=0.000), marital status (p=0.000) and occupation (p=0.000). Significant correlation between clinical diagnosis and histopathological finding was found (r= 0.7, p=0.00). Conclusion: Hysterectomy is most common surgical modality in gynecology. Adenomyosis is most common histopathological finding in patients undergone hysterectomy for benign condition. All hysterectomy specimens should be subjected to pre-operative and post-operative histopathological examination for accurate diagnosis and management in benign conditions.
Background and Aim: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapid emergence postured significant challenges on the health system in recent years. The early detection of cases is thought to be critical in preventing this pandemic by coronavirus disease (COVID-19), especially important in the obstetrical population due to theirs numerous interactions with another parturient when hospitalized for delivery. Therefore, the present study aimed to assess the COVID antigen test performance in COVID-positive obstetrics patients. Materials and Methods: This cross-sectional study was conducted on 1296 Covid-19 asymptomatic women admitted to the Obstetrics and Gynaecology Department of Muhammad Teaching Hospital & Medical College, Peshawar and Fauji Foundation Hospital, Rawalpindi for the duration of six months from February 2021 to July 2021. Antigen-based test rapid diagnostic test (RDT) was used for screening out COVID-19 positive obstetrics patients or women through nasopharyngeal swabs. Women with negative rapid antigen test results were confirmed with RT-polymers chain reaction test of nucleic acid amplification tests (NAAT). Ethical approval and informed consent were taken from the hospital ethical committee and each individual respectively. All the known positive COVID-19 patients during admission were excluded. SPSS version 24 was used for data analysis. Results: The overall prevalence of rapid antigen-positive tested patients was 13.2% (171/1296). The prevalence of positive tested women through rapid antigen test, Nucleic Acid Amplification Test (NAAT), and RT-PCR were 27 (2.1%), 51 (3.9%), and 93 (7.2%) respectively. Of the total 1296 rapid antigen tests, 27 were positive, and the false-negative confirmed positive by NAAT was 144.Thus the sensitivity of the rapid antigen test was 15.8% and the negative predictive value was 93.7%. Of the total 298 Nucleic Acid Amplification Tested had sensitivity and negative predictive value of 89.6% and 99.06% respectively. RT-PCR was carried out on 972 patients, positive diagnosed cases were 36 while 15 were initially negative and were positive with the test was repeated. The sensitivity and negative predictive value was 71.45% and 95.8% respectively. Conclusion: Our study found that Ag-RDT plays a significant role in SARS-CoV-2 early detection in infected individuals, with high specificity and sensitivity to disease infectious stage, whether symptomatic or asymptomatic, and can be used as a decision supported tool. Early detection of COVID-19 status in women admitted for delivery could benefit neonatal protection care. Keywords: Covid-19; Rapid antigen test; RT-PCR test
Objective: The study's objective is to examine the effectiveness of syntometrine and oxytocin in actively managing the third stage of labour in order to lower the risk of PPH and other undesirable third stage outcomes. Study Design: Randomized/Prospective study Place and Duration: Gynae & Obs department of Combined Military Hospital Peshawar for the duration from 1st June 2021 to 30th November 2021. Methods: This study comprised of 140 females of third stage labour. Age of the females was 18-40 years. After getting informed written consent detailed demographics of enrolled cases were recorded. Patients were equally divided in two groups. Group I had 70 patients and received syntometrine (5 IU Synthetic Oxytocin and 0.5 mg ergometrine maleate) and in group II oxytocin was given to 70 females. Outcomes among both groups were recorded in terms of blood loss and postpartum hemorrhage. SPSS 23.0 was used to analyze all data. Results: The mean age of the patients was 28.3±6.18 years and had mean BMI 27.6±11.25 kg/m2. Mean gestational age was 36.11±5.19 weeks. Frequency of primigravida was 80 (57.1%). Frequency of emergency delivery was found in 85 (60.7%) cases while 55 (39.3%) females admitted to OPD. 72 (51.4%) females were from rural areas and 67 (47.8%) cases were educated. We found that mean blood loss in group II was higher 165.1±8.66 ml as compared to group I 118.7±9.39 ml with p value <0.005. There was no any PPH found in group I while in group II PPH found in 3 (4.3%) cases. Frequency of hypertension was higher in group I. We found higher number of adverse outcomes among females of syntometrine group as compared to oxytocin group. Conclusion: In this study we concluded that use of syntometrine in third stage of labour was effective and useful in terms of reduction in blood loss and PPH as compared to oxytocin while frequency of adverse events and hypertension was higher in syntometrine group as compared to oxytocin. Keywords: Pregnant Females, Third Stage Labour, Syntometrine, Oxytocin, Blood Loss
ABSTRACT… Objectives: To compare neonatal outcome in laboring patients having fetal distress on cardiotocography in clear liquor vs meconium stained liquor. Study Design: Cohort study. Setting: Department of Obstetrics and Gynaecology, Military Hospital, Rawalpindi. Period: Six months from 31-01-2016 to 30-07-2016. Patients and Methods: One hundred and eighty two patients (91 in each group) were included in this study. All relevant information was recorded on a preset data collection proforma that included gestational age, cardiotocography (CTG) details, color of liquor and Apgar score at 1 and 5 minutes after birth. In all admitted patients CTG was carried out. Results: The age ranged from 20-40 years of the patients with Mean±SD age of 29.8±6.1 and 30.4±5.7 year in group-A and B, respectively. Regarding Apgar score at 1 minute, 2 (2.1%) babies from group-A and 9 babies (9.8%) from group-B had Apgar score <4. Similarly, Apgar score at 5 minutes, 1 baby (1.1%) from group-A and 10 babies (10.9%) were having Apgar score < 4. Conclusion: Meconium staining with CTG changes is a more significant sign of fetal distress as compared to CTG changes alone.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.