The study was carried out to observe some aspects of hematological changes like Hb concentration, PCV and TC of RBC in different stages of Chronic Renal Failure(CRF) patients suffering from anemia. For this purpose, 65 male CRF patients with anemia and 25 apparently health male (control) subjects of age ranged from 30-50 years were selected randomly from BSMMU out patient department. Hematological parameters and renal creatinine clearance were estimated by usual laboratory technique. Data were analyzed statistically by ANOVA and Pearson's correlation coefficient test. Among the CRF patients 15 were mild, 25 were moderate and 25 were severe CRF patients with anemia. In this study, the mean Hb concentration, PCV and total count of red blood cells were significantly lower in three stages of CRF patients with anemia compared to those of healthy subjects. Again, all of these hematological values were significantly (P< 0.001) lower in moderate and severe CRF patients compared to mild cases and also in severe cases than those of moderate CRF cases with anemia. All the Hematological parameters showed positive correlation with creatinine clearance in all three stages of CRF and it was statistically significant in moderate and severe group. From the present study it may be concluded that CRF patients with anemia had lower hematological indices and the degree of changes depend on severity of renal failure. Key Words: Hemoglobin; Packed Cell Volume; Renal Failure DOI:10.3329/jbsp.v2i0.983 J Bangladesh Soc Physiol. 2007 Dec;(2): 38-41.
Hematological abnormalities are frequently encountered in patients with SLE. It was aimed to study the pattern and frequency of hematological abnormalities in patients with SLE. Forty patients were prospectively analyzed who were suffering from SLE in the CMCH over a period of one year. All patients were evaluated according to the case record form with particular reference to hematological manifestations. Most patients were females in the child bearing age. Hematological manifestations were documented in87.5% of patients. Anemia was the most common hematological abnormality detected (57.5%). Iron deficiency anemia(IDA) 60%, Anemia of chronic disease(ACD) 26.9% and Autoimmune hemolytic anemia(AIHA) 8.7 % were the most common cause of anemia detected. The data demonstrated that while hematological manifestations are very common in SLE but they are rarely life threatening.
Background: Anemia is one of the most consistent and severe hematological complication in chronic renal failure (CRF) patients. Lowered Hb concentration, packed cell volume (PCV) and total count (TC) of red blood cell (RBC) in such patients and the relation of changes of these values with the severity of renal failure is important to detect anemia earlier.. Subjects and Methods: The present study has been designed to observe hemoglobin concentration, PCV and TC of RBC in different stages of CRF patients suffering from anemia. For this purpose, 65 male CRF patients with anemia and 25 healthy male (control) subjects, age ranged from 30-50 years were selected randomly from BSMMU outpatient department. Hb concentration, PCV, TC of RBC and creatinine clearance were estimated by usual laboratory technique. Data were analyzed statistically by ANOVA and Pearson's correlation coefficient test. Among 65 CRF patients, 15 were mild, 25 were moderate and 25 were severe with renal failure associated with anemia. Results: In this study, the mean Hb concentration, PCV and total count of RBCs were significantly lower in three stages of CRF patients with anemia compared to those of healthy subjects. Again, these hematological values were significantly (P < 0.001) lower in moderate and severe CRF patients compared to mild cases and also in severe cases than those of moderate CRF cases with anemia. All the hematological parameters showed positive correlation with creatinine clearance in three stages of CRF and it was statistically significant in moderate and severe group. Conclusion: From the present study it may be concluded that CRF patients with anemia had lower Hb concentration, PCV and TC of RBC and the degree of changes depend on severity of renal failure.
We report a case of severe malaria (cerebral malaria) developing aspiration pneumonia and acute renal failure in a 17-year-old student after returning from malarial hyper endemic zone. The infecting organism was Plasmodium falciparum. Treatment with intravenous quinine and haemodialysis for kidney failure and broad spectrum antibiotic for aspiration pneumonia caused complete recovery of the patient.
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