Background:Patients who undergo cardiac surgery appear to be at increased risk for the development of Nosocomial infections (NIs). The development of antibiotic-resistant infections has been associated with significantly greater hospital mortality rates compared to similar infections caused by antibiotic-sensitive pathogens.Objectives:The purpose of this study is survey of Nis and antibiotic resistance patterns of causative bacteria among patients who underwent open heart surgery in the north of Iran during a 2-year period between September 2012 and September 2014.Methods:In this cross-sectional study we evaluated 187 patients that underwent open heart surgery with NIs. Demographic feature, clinical characteristics and risk factors of each infection were recorded. The antibiotic susceptibility test was performed using the Minimum inhibitory concentration (MIC) method according to the standard protocol of Clinical & Laboratory Standards Institute (CLSI). Detection of Extended-spectrum beta-lactamase (ESBL) producing bacteria was performed by the double-disk synergy (DDS) test; also Methicillin-resistant Staphylococcus (MRSA) strains were identified by MRSA Screen Agar. The collected data were analyzed using the SPSS software (ver. 16) and, descriptive statistics were used.Results:Out Of total of 2253 hospitalized patients who underwent open heart surgery, 187(5.05%) patients had NIs. 51.9% of the patients were female. The rates of surgical site infection (SSI), respiratory tract infection, endocarditis, Urinary tract infection (UTI), blood Infection and mediastinitis were 27.80, 25.66%, 17.64, 17.11% 8.55% and 3.20% respectively. E.coli and S.aureus were the most causative agents of NIs. The rate of ESBL-producing bacteria was 14.28- 71.42% among enterobacteriaceae and the rate of MRSA was 54.2% among S.aureus strains. All isolated Acinetobacter.spp were Multi-drug resistance (MDR).Conclusions:We showed that the rate of NIs among these high-risk patients was in the average level. But the emergence of MRSA and ESBL bacteria is increasing in our region.

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In this study, polyolefin elastomer (POE) foams were prepared without any curing agent using a single-step foaming technique. The effect of azodicarbonamide (ADC) content as a chemical foaming agent on the foams’ morphology and mechanical properties was studied using scanning electron microscopy (SEM), mechanical properties (tension and compression) and hardness. The results showed that increasing the ADC content from 2 to 3, 4 and 5 phr (parts per hundred rubber) decreased the foam density from 0.75 to 0.71, 0.65 and 0.61 g/cm3, respectively. The morphological analysis revealed that increasing the ADC content from 2 to 4 phr produced smaller cell sizes from 153 to 109 µm (29% lower), but a higher cell density from 103 to 591 cells/mm3 (470% higher). However, using 5 phr of ADC led to a larger cell size (148 µm) and lower cell density (483 cells/mm3) due to cell coalescence. The tensile modulus, strength at break, elongation and hardness properties continuously decreased by 28%, 21%, 16% and 14%, respectively, with increasing ADC content (2 to 5 phr). On the other hand, the compressive properties, including elastic modulus and compressive strength, increased by 20% and 64%, respectively, with increasing ADC content (2 to 5 phr). The tensile and compression tests revealed that the former is more dependent on foam density (foaming ratio), while the latter is mainly controlled by the cellular structure (cell size, cell density and internal gas pressure). In addition, 2D SEM images were used to simulate the foams’ real 3D structure, which was used in finite element methods (FEM) to simulate the stress–strain behavior of the samples at two levels: micro-scale and macro-scale. Finally, the FEM results were compared to the experimental data. Based on the information obtained, a good agreement between the macro-scale stress–strain behavior generated by the FEM simulations and experimental data was obtained. While the FEM results showed that the sample with 3 phr of ADC had the lowest micro-scale stress, the sample with 5 phr had the highest micro-scale stress due to smaller and larger cell sizes, respectively.