No abstract

No abstract

The modified freeze-thaw process enabled to minimize the temperature gradient within the large cryogel phantoms during the freeze-thaw cycle. The results of this study can help to fill the gaps in the scientific literature with regard to developing homogeneous phantoms for medical imaging. This work also provides a solid foundation for future studies in this field and could facilitate formulating new hydrogels to replicate the viscoelastic properties of soft tissues.

Tissue-mimicking phantoms with well-defined properties can help in identifying the potential weaknesses in medical imaging systems. Among the imaging systems, magnetic resonance elastography is a new noninvasive technique used to quantify the shear modulus of biological tissues, and therefore has shown promise in studying liver and brain pathologies. Polyvinyl alcohol (PVA) cryogel prepared by the freeze-thaw technique is a potential candidate for mimicking the mechanical properties of soft tissues and has been extensively used as a phantom material. However, large PVA cryogels suffer from variations in properties, partly due to the low thermal conductivity of PVA solution. The loss of homogeneity in cryogel phantoms is also attributed to inhomogeneous thawing rates during the freeze-thaw cycle. We have used a modified freeze-thaw process that imposes multiple isotherms so as to enhance the homogeneity of the produced cryogels. In addition, we have developed a finite-element modeling tool (a virtual controller) to optimize the temperature profile during the freeze-thaw cycle. Our experimental validations demonstrated the potential of the virtual controller in predicting the optimal temperature profile for the freeze-thaw process (phantom diameters: 60 and 100 mm). A robust simulation framework can fill the gap in the scientific literature with regard to phantom design for medical imaging and will help to reduce phantom development time and cost.

In 2017, a blowout and explosion occurred in a drilling oilwell in the Middle East. After drilling to the depth of 2,610 m, tripping was decided in order to change the bit. When the crew were pulling the drill string out of the hole with the drill-string being at the depth of 1332 m, blowout and explosion occurred. The well was a development well drilling almost horizontally (82 degrees inclination angle) into a highly-pressured gas-cap and oil pay-zone of the oilfield. In this work, following a brief explanation of the root causal factors of the incident, we give an account of the blowout control methods applied to put an end to the blowout. Both the top-kill method and the bottom-kill method by relief well drilling, were simultaneously implemented to control the blowout. Finally, the blowout was successfully controlled by the bottom-kill after 58 days. During top-kill operations, all equipment was cleared away and this contributed to proceeding to permanent abandonment immediately after the relief well success. Finally, the adverse effect of the blowout on the environment (HSE) was qualitatively discussed.