Eight new mixed ligands metal complexes have been prepared by the reaction of Fe(II), Co(II), Ni(II) and Cu(II) with (1:1:1 molar ratio) of ciprofloxacin -eugenol or levofloxacin -eugenol mixed ligands in alkaline medium. The coordination of the mixed ligands toward metal ions has been anticipated in the light of elemental analysis, molar conductance, spectral infrared (IR), ultraviolet-visible (UV-Vis) and magnetic measurements were bidentate ligands. Electronic and magnetic data suggested the octahedral configuration for all these new complexes. The molar conductance data for the metal complexes show nonelectrolytic behaviour in DMF solvent and non-electrolytic properties, also they were no conducting electrical current. The biological activity of the prepared complexes was studied with positive and negative Gram-positive bacteria and good antibacterial results.
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