Acral myxoinflammatory fibroblastic sarcoma is a rare low-grade malignant soft tissue tumor, usually observed in the extremities of middle-aged patients. We report a case involving the third finger of the left hand of a middle-aged man. The tumor showed a nodular architecture, with cellular areas, occasional foci of hyalinized fibrosis, and hypocellular areas with a myxoid background. Various neoplastic cells were identified including spindled or rounded epithelioid cells and occasional bizarre giant cells, morphologically mimicking ganglion cells. Tumor cells were strongly immunoreactive for vimentin and variably positive for CD68 and CD34. The tumor was completely removed, without further treatment.
Teratocarcinosarcoma is a rare and aggressive malignant tumor of uncertain histogenesis. It presents <1% of all cancers and ~3% of malignant tumors of the head and neck. It arises commonly from the nasal cavity and paranasal sinuses. To the best of our knowledge, only one case has been reported in the oral cavity. A 46-year-old woman presented with 3-week history of a rapidly growing tumor in the inner side of the left cheek. Physical examination revealed an ulcerating mass measuring 4 × 3.5 cm. An excisional biopsy was performed. Histological analysis revealed a teratocarcinosrcoma. The patient was treated by combined chemotherapy and radiation therapy. No recurrence was noted 6 months after treatment. The prognosis is poor.
La fréquence et le mauvais pronostic des cancers bronchopulmonaires justifient les nombreuses études consacrées à cette pathologie. Pour avoir une approche épidémiolo-gique et anatomoclinique de ces affections, nous avons réalisé une étude rétrospective d'une série de 163 cas colligés au service d'anatomie pathologique de l'hôpital militaire d'instruction Mohamed-V de Rabat (HMIM-V) [de 1994 à 2003]. Il ressort ainsi de notre étude une augmentation générale du nombre de cas diagnostiqués chaque année avec une tendance à l'inversion des fréquences durant les dernières années : l'adé-nocarcinome et le carcinome à petites cellules (CPC) deviennent plus fréquents ; un âge moyen global de 53 ans ; une large prédominance masculine (93 %) avec un sex-ratio de 12,1. Les symptômes ayant motivé la consultation sont dominés par la toux, la douleur thoracique et l'hémoptysie. La nocivité reconnue du tabac est retrouvée dans 54 % des cas, cela pourrait souligner le rôle du tabagisme passif et/ou d'autres facteurs étiologiques. Les carcinomes non à petites cellules représentent 60,8 % avec une large prédominance du carcinome épider-moïde (37,4 %) avec un âge moyen de 54 ans, suivi par l'adé-nocarcinome (21,4 %) avec un âge moyen de 48 ans, puis le carcinome à grandes cellules (2 %) avec un âge moyen de 53 ans. Les carcinomes à petites cellules et assimilés représen-tent 11 %, avec un âge moyen de 63 ans. L'immunohistochimie est généralement nécessaire pour préciser le type histologique d'une forme peu différenciée (8,6 % de notre série). Ainsi, le pathologiste dans ce domaine doit se tenir informé continuellement des progrès sur l'histogenèse de ces affections et l'apport des méthodes de recherche et de prises en charge nouvelles. Pour citer cette revue : J. Afr. Cancer 3 (2011). Mots clés Poumon · Carcinome · Type histologique · Cancer bronchopulmonaireAbstract The frequency and the bad prognosis of broncopulmonary cancers justify the numerous studies dedicated to this pathology. To have an epidemiological and a clinical approach to these disorders, we performed a retrospective study of a series of 163 cases of bronco-pulmonary cancers collected from the anatomy pathology department of the Mohamed V Military Hospital of Instruction in Rabat (1994Rabat ( to 2003. We observed in general an increase in the number of diagnosed cases every year, with a trend reversal during the later years: the adenocarcinoma and the small cells carcinoma (CPC) became more frequent than the squam cells carcinoma; a mean age of intervening of 53 years; a large masculine predominance (93%) with a high sex-ratio (12.1). The symptoms that prompted the consultation are dominated by cough, thoracic pain and haemoptysis. The effect of tobacco was found in 54% of the cases, underlining the probable role of passive tobacco and/or of other etiologic factors. Non-small cells carcinomas represent 60.8%, of which squam cells carcinoma constitute a predominant portion (37.4%), with a mean age of 54 years, followed by adenocarcinoma (21.4%), with a mean age of...
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