Summary StatementMerzouga sand dunes were among the Moroccan extreme environments. This ecosystem is relatively unexplored and present habitat to the search for Actinobacteria with potential antimicrobial activities and biotechnological applications. Biology Open • Accepted manuscriptby guest on April 27, 2019 http://bio.biologists.org/ Downloaded from Abstract:The absence of new antibiotics is guiding more and more researchers to specific ecosystems.One hundred sixty-three Actinobacteria isolates were isolated from Merzouga sand and

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