Background:Hypertension (HTN) and Diabetes mellitus (DT2) are frequently underdiagnosed in Africa. The present study was carried out to assess the situation in the urban commune of Dubreka.Methods:Prospective and transversal, the study was focused on 287 participants (174 females; 113 males). HTN and DT2 were defined according to the blood pressure standards of at least 140/90 mm Hg and glycemia at least 1.26 g /l, respectively [1,2].Results:Overall rate was 74% (211/287) for HTN and 37% (105/287) for DT2. Both sex were concerned: 75% HTN and 36% DT2 in females vs 71% HTN and 38% DT2 in males. Salty diet and sedentary lifestyle were common. In females, 39% were overweight and 34% were obese. The association HTN and DT2 have been noted in 46% (96/211) among the hypertensive and 91% (96/105) among the diabetics. Of the 96 diabetic hypertensives, 45% were overweight (43/96), and 27% (26/96) were obese. In hypertensive, 85% (179/211) were aware of their status and 7% (13/179) were undergoing treatment without any control. In diabetics, 22% (23/105) were aware of their diagnosis with 30% (7/23) on treatment without any control. Conventional treatment of the few patients has generally focused on generic metformin and glibenclamide for diabetes and nifedipine for hypertension which in health centers cost from 15,000 GNF to 25,000 GNF (3,45$ to 5,75$). Such financial inaccessibility to conventional medicine partly justifies the frequent use of medicinal plants either alone or in association with conventional medicines.Conclusion:Hypertension and diabetes remain a concern in Dubréka where low rates of awareness, treatment and control were noticed.REFERENCES2018 ESC/ESH Guidelines for the management of arterial hypertension: J Hypertens. 2018 Oct;36(10):1953–2041.[2019] ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. European Heart Journal (2020) 41, 255–323.
As part of a validation program of antimalarial traditional recipes, an ethnotherapeutic approach was applied in Dionfo, a meso-endemic Guinean rural area where conventional health facilities are insufficient. A prevalence investigation indicated a malarial burden of 4.26%. Ethnomedical and ethnobotanical surveys led to a collection of 63 plant species used against malaria from which Terminalia albida (Combretaceae) was one of the most cited. Ethnotherapeutic evaluation of a remedy based on T. albida was applied to 9 voluntary patients suffering from uncomplicated malaria. Treatment of 7 to 14 days led to an improvement of clinical symptoms and a complete parasite clearance achievement of 8/9 patients without side effects. In addition to antiplasmodial activity in vitro and in vivo previously described, this study indicates an efficacy to support the antimalarial traditional use of T. albida, which could constitute a first-aid treatment
when access to other medicines is delayed in the Dionfo community. Ethnotherapeutical investigation could be a valuable approach to guide subsequent investigations on traditional remedies.
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