The primary focus of this paper is to study the film cooling performance for a row of cylindrical holes each supplemented with two symmetrical anti vortex holes which branch out from the main holes. The anti-vortex design was originally developed at NASA-Glenn Research Center by Dr. James Heidmann, co-author of this paper. This “anti-vortex” design is unique in that it requires only easily machinable round holes, unlike shaped film cooling holes and other advanced concepts. The hole design is intended to counteract the detrimental vorticity associated with standard circular cross-section film cooling holes. The geometry and orientation of the anti vortex holes greatly affect the cooling performance downstream, which is thoroughly investigated. By performing experiments at a single mainstream Reynolds number of 9683 based on the free stream velocity and film hole diameter at four different coolant-to-mainstream blowing ratio of 0.5, 1, 1.5, 2 and using the transient IR thermography technique, detailed film cooling effectiveness and heat transfer coefficients are obtained simultaneously from a single test. When the anti vortex holes are nearer to the primary film cooling holes and are developing from the base of the primary holes, better film cooling is accomplished as compared to other anti vortex hole orientations. When the anti vortex holes are laid back in the upstream region, film cooling diminishes considerably. Although an enhancement in heat transfer coefficient is seen in cases with high film cooling effectiveness, the overall heat flux ratio as compared to standard cylindrical holes is much lower. Thus cases with anti vortex holes placed near the main holes certainly show promising results.

The present study is an experimental investigation of film cooling from cylindrical holes embedded in transverse trenches. Different trench depths are considered with two trench widths. Trench holes can occur when blades are coated with thermal barrier coating (TBC) layers. The film-hole performance and behavior will be different for the trench holes compared to standard cylindrical holes that are flush with the surface. The trench width and depth depend on the mask region and the thickness of the TBC layer. Detailed heat transfer coefficient and film effectiveness measurements are obtained simultaneously using a single test transient IR thermography technique. The study is performed at a single mainstream Reynolds number based on freestream velocity and film-hole diameter of 11,000 at four different coolant-to-mainstream blowing ratios of 0.5, 1.0, 1.5, and 2.0. The results show that film effectiveness is greatly enhanced by the trenching due to the improved two-dimensional nature of the film and lateral spreading. The detailed heat transfer coefficient and film effectiveness contours provide a clear understanding of the jet-mainstream interactions for different hole orientations. Computational fluid dynamics simulation using FLUENT was also performed to determine the jet-mainstream interactions to better understand the surface heat transfer coefficient and film effectiveness distributions.

The primary focus of this paper is to study the film cooling performance for a row of cylindrical holes each supplemented with two symmetrical antivortex holes, which branch out from the main holes. The antivortex design was originally developed at NASA-Glenn Research Center by James Heidmann, coauthor of this paper. This “antivortex” design is unique in that it requires only easily machinable round holes, unlike shaped film cooling holes and other advanced concepts. The hole design is intended to counteract the detrimental vorticity associated with standard circular cross-section film cooling holes. The geometry and orientation of the antivortex holes greatly affect the cooling performance downstream, which is thoroughly investigated. By performing experiments at a single mainstream Reynolds number of 9683 based on the freestream velocity and film hole diameter at four different coolant-to-mainstream blowing ratios of 0.5, 1, 1.5, and 2 and using the transient IR thermography technique, detailed film cooling effectiveness and heat transfer coefficients are obtained simultaneously from a single test. When the antivortex holes are nearer the primary film cooling holes and are developing from the base of the primary holes, better film cooling is accomplished as compared to other antivortex hole orientations. When the antivortex holes are laid back in the upstream region, film cooling diminishes considerably. Although an enhancement in heat transfer coefficient is seen in cases with high film cooling effectiveness, the overall heat flux ratio as compared to standard cylindrical holes is much lower. Thus cases with antivortex holes placed near the main holes certainly show promising results.

Film cooling performance is studied for cylindrical holes embedded in craters. Different crater geometries are considered for a typical crater depth. Cratered holes may occur when blades are coated with thermal barrier coating layers by masking the hole area during TBC spraying resulting in hole surrounded by TBC layer. The film performance and behavior is expected to be different for the cratered holes compared to standard cylindrical holes. Detailed heat transfer coefficient and film effectiveness measurements are obtained simultaneously using a single test transient IR thermography technique. The study is performed at a single mainstream Reynolds number based on free-stream velocity and film hole diameter of 11000 at four different coolant-to-mainstream blowing ratios of 0.5, 1.0, 1.5 and 2.0. The results show that film cooling effectiveness is slightly enhanced by cratering of holes but a substantial increase in heat transfer enhancement negates the benefits of higher film effectiveness. Three different crater geometries are studied and compared to a baseline flush cylindrical hole, a trenched hole, and a typical diffuser shaped hole. CFD simulation using Fluent was also performed to determine the jet-mainstream interactions associated with the experimental surface measurements.

The present study is an experimental investigation of film cooling from cylindrical holes embedded in transverse trenches. Different trench depths are considered with two trench widths. Trench holes can occur when blades are coated with thermal barrier coating (TBC) layers. The film hole performance and behavior will be different for the trench holes compared to standard cylindrical holes that are flush with the surface. The trench width and depth depends on the mask region and the thickness of the TBC layer. Detailed heat transfer coefficient and film effectiveness measurements are obtained simultaneously using a single test transient IR thermography technique. The study is performed at a single mainstream Reynolds number based on free-stream velocity and film hole diameter of 11000 at four different coolant-to-mainstream blowing ratios of 0.5, 1.0, 1.5 and 2.0. The results show that film effectiveness is greatly enhanced by the trenching due to improved two dimensional nature of the film and lateral spreading. The detailed heat transfer coefficient and film effectiveness contours provide a clear understanding of the jet-mainstream interactions for different hole orientations. CFD simulation using Fluent was also performed to determine the jet mainstream interactions to better understand the surface heat transfer coefficient and film effectiveness distributions.

Film cooling performance is studied for cylindrical holes embedded in craters. Different crater geometries are considered for a typical crater depth. Cratered holes may occur when blades are coated with thermal barrier coating layers by masking the hole area during thermal barrier coating (TBC) spraying, resulting in a hole surrounded by a TBC layer. The film performance and behavior is expected to be different for the cratered holes compared to standard cylindrical holes. Detailed heat transfer coefficient and film effectiveness measurements are obtained simultaneously using a single test transient IR thermography technique. The study is performed at a single mainstream Reynolds number based on freestream velocity and film-hole diameter of 11,000 at four different coolant-to-mainstream blowing ratios of 0.5, 1.0, 1.5, and 2.0. The results show that film cooling effectiveness is slightly enhanced by cratering of holes, but a substantial increase in heat transfer enhancement negates the benefits of higher film effectiveness. Three different crater geometries are studied and compared to a base line flush cylindrical hole, a trenched hole, and a typical diffuser shaped hole. Computational fluid dynamics simulation using FLUENT was also performed to determine the jet-mainstream interactions associated with the experimental surface measurements.

Introduction: Multimorbidity is defined as the co-occurrence of two or more chronic conditions in the same individual. Type 2 Diabetes Mellitus rarely occurs without coexisting diseases. With an increasing elder population and longevity, elder adults have a higher prevalence of chronic morbidity, thus increasing the chances of experiencing more than one non-communicable chronic condition, where the impact of multimorbidity is greater than the cumulative effect of the single condition. The study aimed to find out the prevalence of multimorbidity in diabetic patients admitted to a tertiary care centre. Methods: A descriptive cross-sectional study was conducted utilising hospital records of patients with type 2 diabetes mellitus admitted to the Department of Medicine from 1 April 2021 to 1 April 2022. Ethical clearance was obtained from the Institutional Review Committee of the same institute (Reference number: 12082022/07). The diagnosed cases of type 2 diabetic patients aged more than 18 years and confirmed with serum glucose levels were included in the study. Convenience sampling was used. Point estimate and 95% Confidence Interval were calculated. Results: Out of the 107 diabetic patients, multimorbidity was present in 75 patients (70.10%) (61.42-78.77, 95% Confidence Interval). Conclusions: The prevalence of multimorbidity is higher than the similar studies done in similar settings.

Toxic epidermal necrolysis is a potentially life-threatening dermatological condition whose pathogenesis and exact treatment are not yet known. Drugs like anticonvulsants, allopurinol and non-steroidal anti-inflammatory drugs like etoricoxib, a selective cyclo-oxygenase-2 inhibitor prescribed for pain management are associated with a high risk of toxic epidermal necrolysis. It is also associated with immunodeficiency and dysregulated immune reactions like systemic lupus erythematosus, an autoimmune disease in which organs and cells undergo damage initially mediated by tissue binding auto-antibodies and immune complexes. Here, a 34 year old lady was presented in emergency with multiple maculopapular rashes over the neck and trunk region after treatment with etoricoxib for osteoarthritis of the left foot.