Hospitalisations for chronic obstructive pulmonary disease (COPD) exacerbations are characterised by a significant worsening of the respiratory symptoms which can impair the health status (HS). However little is known on the HS behaviour during such events. Prospective study evaluating the validity of the Clinical COPD Questionnaire (CCQ) as a HS measure in hospitalisations for COPD exacerbations. The CCQ total score (CCQ-T) correlated with EQ-VAS (-0.51, p < 0.0001), was able to discriminate between longer and shorter duration hospitalisation (CCQ-T 3.83 vs 3.03, respectively p = 0.001), had a Cronbach-α of 0.86, and improved significantly over the hospitalisation period (CCQ-T on day 7 of hospitalisation 2.55 vs 3.77 at baseline, p < 0.0001). CCQ is an excellent tool for the assessment of the HS dynamics in hospitalisations for COPD exacerbations.
sponse options; 4) ease of completing the questionnaire; 5) relevancy of the items; 6) formatting (e.g., design and placement of instructions, font, placement of items on page); and 7) identification of new concepts (e.g., functional areas or activities that patients consider relevant and not represented by existing items). RESULTS: Twenty COPD patients were interviewed: 12 (60%) males; mean age ϭ 63.0 Ϯ 11.3 years; 14 (70%) Caucasian; 12 (60%) retired; mean FEV 1 ϭ 1.5 Ϯ 0.5 liter; FEV 1 % predicted ϭ 48.4 Ϯ 13.1. Content of the FPI-SF was seen as comprehensive and represented activities participants found important and often difficult to perform. Participants understood the instructions, items, and response options as intended. No new concepts were identified. Two minor formatting changes were suggested to improve clarity. CONCLUSIONS: These results, together with its development history and previously tested quantitative properties, suggest the FPI-SF is content valid for use in clinical studies of COPD.
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