PRS61 Age has No Significant Impact on Health-Related Quality of Life in Patients Hospitalized for COPD Exacerbations

Abstract

sponse options; 4) ease of completing the questionnaire; 5) relevancy of the items; 6) formatting (e.g., design and placement of instructions, font, placement of items on page); and 7) identification of new concepts (e.g., functional areas or activities that patients consider relevant and not represented by existing items). RESULTS: Twenty COPD patients were interviewed: 12 (60%) males; mean age ϭ 63.0 Ϯ 11.3 years; 14 (70%) Caucasian; 12 (60%) retired; mean FEV 1 ϭ 1.5 Ϯ 0.5 liter; FEV 1 % predicted ϭ 48.4 Ϯ 13.1. Content of the FPI-SF was seen as comprehensive and represented activities participants found important and often difficult to perform. Participants understood the instructions, items, and response options as intended. No new concepts were identified. Two minor formatting changes were suggested to improve clarity. CONCLUSIONS: These results, together with its development history and previously tested quantitative properties, suggest the FPI-SF is content valid for use in clinical studies of COPD.

Systematic Review of Humanistic and Economic Burden of Symptomatic Chronic Obstructive Pulmonary Disease

“…An increase in the severity of respiratory symptoms was associated with a corresponding decline in the HRQoL of patients [4,5,[25][26][27][28]. Antoniu and colleagues evaluated HRQoL by categorising patients on the basis of symptom levels (mild, moderate, and severe).…”

“…Antoniu and colleagues evaluated HRQoL by categorising patients on the basis of symptom levels (mild, moderate, and severe). Patients experiencing severe sputum and cough had significantly higher fatigue and disability levels and significantly lower energy levels compared with patients with mild symptoms [28]. In contrast, a study by Al Moamary and colleagues revealed no significant differences in HRQoL in patients experiencing cough and wheezing evaluated using CAT and Chronic Respiratory Questionnaire-Self-Administered Standardized (CRQ-SAS) scores [4].…”

“…A longer duration of illness, longer hospital stay, and higher number of hospitalisations were other important factors influencing HRQoL in patients with symptomatic COPD [25,28,63,64]. HRQoL also deteriorated with an increase in general respiratory symptoms and their severity.…”