Necrotizing otitis externa is an uncommon but severe infectious disease of the external auditory canal. Patients at risk are those immunodepressed or having diabetes. The causal germ is often Pseudomonas aeruginosa. Over a period of 10 years (1997-2006), we treated 19 patients: 94.7% had diabetes (insulin dependent in 6 cases). The causal germ was P. aeruginosa in 59% of cases. The pretherapeutic work-up included a computed tomography and a scintigraphy practiced in order to confirm diagnosis and assess the extension. Medical treatment was based on a parenteral antibiotic therapy using a third-generation cephalosporin and a fluoroquinolones. Local treatment of the auditory canal including cleaning and application of antimicrobial agents was performed in all the cases. Surgical debridement of soft tissue and infected bone was performed in one patient who did not respond to medical management. Repeated scintigraphies with gallium were used to follow the course under treatment in only three cases. We had a 89.4% cure rate with only three cases of recurrence. We reviewed the data in the literature on necrotizing otitis externa and present the important diagnostic, imaging, and therapeutic aspects of the disease.
RESUME L'angiomyxome agressif est une tumeur mésenchymateuse développée aux dépens du tissu conjonctif avec un site de prédilection pour les parties molles du périné féminin. Cette tumeur croit progressivement mais n'est pas métastatique. Le traitement indiqué actuellement est l'exérèse chirurgicale large sans conséquences fonctionnelles lourdes. La tumeur a une tendance à la récidive locale, qui est fréquente, liée à la difficulté d'une exérèse initiale complète. Les auteurs rapportent ici le cas d'un angiomyxome agressif de la joue, qui a été traité par chirurgie et chimiothérapie. Les aspects cliniques, histologiques et thérapeutiques de la tumeur ont été discutés. Mots-clés : L'angiomyxome agressif, tumeur mésenchymateuse, exérèse, récidive. SUMMARY An aggressive angiomyxoma is a mesenchymal tumour arising from connective tissues with a predilection for the female pelvic soft parts. It is slow growing but non-metastasizing neoplasm. The treatment, recommended at present, is wide local excision without causing significant morbidity. The tumor has a tendency to local recurrence, which is common and related to inadequate primary complete excision. The authors report here a case of aggressive angiomyxoma of the jaw, that was treated by surgery and chemotherapy. The clinical and pathologic features of this tumor are discussed
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