Preparation of hydroxyapatite (HA) through natural sources, such as fish scales or synthetic HA produced from the chemical reaction has been widely used as biomedical materials because HA is bioactive, non-toxic and osteoconductive with a crystallographic structure almost similar to that of the bone mineral. In addition, HAwith particle size < 10 microns is classified as common inorganic filler used to improve the mechanical properties and biocompatibility of polymer composites. The purpose of this review is to collect information related to HA, and to provide readers with information about synthesis methods, advantages of hydroxyapatite as biomaterial,biomedical applications of polymer/HA composites.
The aims of this study were to prepare natural hydroxyapatite from fish scales (FsHAp) for potential use as a filler in polymer. The FsHAp was prepared from Tilapia fish scales using thermal method. The FsHAp was milled for 48 h and dried by spray method. The morphology was characterized using field emission scanning electron microscope (FESEM) which showed irregular shape of FsHAp particles with particle size around 7 μm. The analysis of FsHAp was carried out using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) to confirm chemical structure of FsHAp.
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