Aminocarboxylic acids (hydrazinocarboxylic acids) and esters Q 0440Efficient Three-Step Sequence for the Deamination of α-Aminoesters. Application to the Synthesis of CysLT1 Antagonists. -The strategy is applied to the deamination of a variety of structurally diverse α-aminoesters (I) and can be extended to the preparation of the heterocyclic system (VIII), which represents the title antagonists.-(GONZALEZ, A.; PEREZ, D.; PUIG, C.; RYDER, H.; SANAHUJA, J.; SOLE, L.; BACH*, J.; Tetrahedron Lett. 50 (2009) 23, 2750-2753; Dep. Med. Chem., Almirall, E-08960 St. Just Desvern, Spain; Eng.) -Mais 38-078
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