Abstract. Over the last decade the number of toxicants increased that affect the safety of raw materials and food, simultaneously with it, the time increases and methods are complicated for their determination. The complete analysis of the quality and food safety for all normalized indicators is quite costly. In this regard, integrated quality control by biotesting is relevant. The purpose of work -experimental evaluation methods: determination of acute toxicity by the culture of ciliates Tetrahymena pyriformis for control of the safety of raw materials and food products in the process of monitoring. The objects of the study were fresh herbs (parsley, dill), wild boar, duck, beef, mincemeat (beef, pork), fish (pike). The paper presents the results of studies evaluating the methods by biotesting for control of food safety in the process of monitoring. In most cases, the correlation results showed determination of toxicity by methods to determining acute toxicity on ciliates, and also content specific anthropogenic and natural toxicants. The method for determining acute toxicity by ciliates is sufficiently rapid, does not require using of experimental animals or costly equipment and has prospects for acceleration of safety control of raw materials and food products.
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