small facial mass. Clinical findings included a small triangular face with frontal bossing, blue sclerae, thin lips with downturned corners, retromicrognathia, and limb asymmetry. Weight and height at admission were less than 5th percentile (Weight was 3.9 kg and size 56 cm); her head circumference grew normally along the 75th percentile. Observation 2 A male Infant was hospitalised at the age of 1 year and 4 months. Physical examination showed growth deficiency: Weight: 7.1 Kg (<5th percentile), size: 72 cm, head cirumference: 46 cm (25th percentile). The same facial features as the first case was found with body asymmetry, flat and narrow feet and cryptorchidism. Conclusion The diagnosis of this syndrome is based on clinical findings. The treatment is purely symptomatic and growth hormone administration does not achieve the target size. The longterm prognosis, a part the growth, is good.

Background and aims We studied the feto-placental interface, in Pregnancy Induced Hypertension (PIH), to present his specific structural modifications. Method We have studied the microscopical modifications of 68 placentas obtained after delivery for two equal groups representing mothers with PIH and normotensive. The samples obtained by sections were specifically prepared for the study using three types of histological stains. We used optical microscopy for observing mainly the lumen of spiral arteriole and changes in its intimate and medial tunica. Results We registered the following specific structural modifications in the pregnancies with PIH : fibrosis in the middle of the villosity, fibrinoid necrosis, condensation of stromal connective tissue, syncytial layer agglutinations of the villous or intervillous spaces (nodes, buds, or bridges), thrombosis and/or infarction of the spiral vessels and villous capillary endothelial atheromatosis. Conclusions Our study was done to find a better understanding of the histo-logical changes of the preeclamptic feto-maternal interface concerning his role in PIH. The morphological modifications of the feto-placental interface in the PIH represent a marker of the fetal and postnatal hypoxia/ischemia with an immediate and late impact upon their cerebral development.

Background and objectives: The objective of this study was to contribute to the evaluation of the newborn (NB) cry as a means of communication and diagnosis. Materials and Methods: The study implied the recording of the spontaneous cry of 101 NBs with no intrapartum events (control sample), and of 72 NBs with nuchal cord (study sample) from the “Bega” University Clinic of Obstetrics–Gynecology and Neonatology of Timisoara, Romania. The sound analysis was based upon: Imagistic highlighting methods, descriptive statistics, and data mining techniques. Results: The differences between the cry of NBs with no intrapartum events and that of NBs affected by nuchal cord are statistically significant regarding the volume unit meter (VUM) (p = 0.0021) and the peak point meter (PPM) (p = 0.041). Conclusions: While clinically there are no differences between the two groups, the cry recorded from the study group (nuchal cord group) shows distinctive characteristics compared to the cry recorded from the control group (eventless intrapartum NBs group).

Background and Objectives: A topic of greatinterest in the surgical field comprises cost and time reduction operative techniques with high efficiency rates. Thus, the aim of this paper is to evaluate whether a transection of the appendix using only a laparoscopic LigaSure™ device is feasible and, if so, which size of the laparoscopic device is optimal. Materials and Methods: Appendectomy specimens were sealed and cut using LigaSureTM V (5 mm) and LigaSure AtlasTM (10 mm) devices ex vivo. Analysis criteria included handling, resistance to bursting pressure of the appendicular stump (adequacy), eligibility, durability and airtightness. Results: Twenty sealed areas were measured. While the 5 mm instrument was not able to transect the appendix in one attempt in any of the cases, the 10 mm device could be applied successfully without any handling difficulties. The adequacy of the sealed area was rated as complete and dry in all 10 cases using the 10 mm device and as oozing in 8 of the cases using the 5 mm device. There was no leakage in terms of air and liquid tightness using the 10 mm device, in contrast to six sealed segments with air and liquid leakage when using the 5 mm device. The resistance to bursting pressure was on average 285 mmHg and 60.5 mmHg with the 10 mm and 5 mm devices, respectively. The durability and eligibility of the 10 mm device were rated as very sufficient in 9 of 10 cases (1 perforation) in contrast to the 5 mm device, where the sealing in 9 of 10 cases was not sufficient (9 perforations). Conclusions: Using the 10 mm laparoscopic LigaSure™ device for the transection of the appendix seems to be feasible, safe and resistant to 300 mmHg bursting pressure. The 5 mm LigaSure™ instrument is inadequate to seal the appendix in humans.