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Acid-catalyzed ester exchange reactions between diphenyl carbonate and inosine, adenosine, and 5 '-O-tritylinosine have given good yields of the respective nucleoside 2',3'-cyclic carbonates. Prior pro-

Canada and the Medical Research Council (Canada) (Grant MA-1591). f Recipient of a postgraduate scholarship from the National Research Council of Canada. Work done in partial fulfillment of the requirements for the Ph.D. degree. 1 Abbreviations and trivial names are: IMP dehydrogenase, IMP-NAD oxidoreductase (EC 1.2.1.14); Cl-IMP, 6-chloro-9-3-D-ribofuranosylpurine 5'-phosphate. See Biochemistry 5, 1445 (1966).

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