OBJECT The unique and complex biomechanics of the atlantoaxial junction make the treatment of C1–2 instability a challenge. Several screw-based constructs have been developed for atlantoaxial fixation. The biomechanical properties of these constructs have been assessed in numerous cadaver studies. The purpose of this study was to systematically review the literature on the biomechanical stability achieved using various C1–2 screw constructs and to perform a meta-analysis of the available data. METHODS A systematic search of PubMed through July 1, 2013, was conducted using the following key words and Boolean operators: “atlanto [all fields]” AND “axial [all fields]” OR “C1–C2” AND “biomechanic.” Cadaveric studies on atlantoaxial fixation using screw constructs were included. Data were collected on instability models, fixation techniques, and range of motion (ROM). Forest plots were constructed to summarize the data and compare the biomechanical stability achieved. RESULTS Fifteen articles met the inclusion criteria. An average (± SD) of 7.4 ± 1.8 cadaveric specimens were used in each study (range 5–12). The most common injury models were odontoidectomy (53.3%) and cervical ligament transection (26.7%). The most common spinal motion segments potted for motion analysis were occiput–C4 (46.7%) and occiput–C3 (33.3%). Four screw constructs (C1 lateral mass–C2 pedicle screw [C1LM–C2PS], C1–2 transarticular screw [C1–C2TA], C1 lateral mass–C2 translaminar screw [C1LM-C2TL], and C1 lateral mass–C2 pars screw [C1LM–C2 pars]) were assessed for biomechanical stability in axial rotation, flexion/extension, and lateral bending, for a total of 12 analyses. The C1LM–C2TL construct did not achieve significant lateral bending stabilization (p = 0.70). All the other analyses showed significant stabilization (p < 0.001 for each analysis). Significant heterogeneity was found among the reported stabilities achieved in the analyses (p < 0.001; I2 > 80% for all significant analyses). The C1LM–C2 pars construct achieved significantly less axial rotation stability (average ROM 36.27° [95% CI 34.22°–38.33°]) than the 3 other constructs (p < 0.001; C1LM–C2PS average ROM 49.26° [95% CI 47.66°–50.87°], C1–C2TA average ROM 47.63° [95% CI 45.22°–50.04°], and C1LM–C2TL average ROM 53.26° [95% CI 49.91°–56.61°]) and significantly more flexion/extension stability (average ROM 13.45° [95% CI 10.53°–16.37°]) than the 3 other constructs (p < 0.001; C1LM–C2PS average ROM 9.02° [95% CI 8.25°–9.80°], C1–C2TA average ROM 7.39° [95% CI 5.60°–9.17°], and C1LM–C2TL average ROM 7.81° [95% CI 6.93°–8.69°]). The C1–C2TA (average ROM 5.49° [95% CI 3.89°–7.09°]) and C1LM–C2 pars (average ROM 4.21° [95% CI 2.19°–6.24°]) constructs achieved significantly more lateral bending stability than the other constructs (p < 0.001; C1LM–C2PS average ROM 1.51° [95% CI 1.23°–1.78°]; C1LM–C2TL average ROM −0.07° [95% CI −0.44° to 0.29°]). CONCLUSIONS Meta-analysis of the existing literature showed that all constructs provided significant stabilization in all axes of rotation, except for the C1LM–C2TL construct in lateral bending. There were significant differences in stabilization achieved in each axis of motion by the various screw constructs. These results underline the various strengths and weaknesses in biomechanical stabilization of different screw constructs. There was significant heterogeneity in the data reported across the studies. Standardized spinal motion segment configuration and injury models may provide more consistent and reliable results.

Background: Computer-assisted solutions are changing surgical practice continuously. One of the most disruptive technologies among the computer-integrated surgical techniques is Augmented Reality (AR). While Augmented Reality is increasingly used in several medical specialties, its potential benefit in orthopedic surgery is not yet clear. The purpose of this article is to provide a systematic review of the current state of knowledge and the applicability of AR in orthopedic surgery. Methods: A systematic review of the current literature was performed to find the state of knowledge and applicability of AR in Orthopedic surgery. A systematic search of the following three databases was performed: "PubMed", "Cochrane Library" and "Web of Science". The systematic review followed the Preferred Reporting Items on Systematic Reviews and Meta-analysis (PRISMA) guidelines and it has been published and registered in the international prospective register of systematic reviews (PROSPERO). Results: 31 studies and reports are included and classified into the following categories: Instrument / Implant Placement, Osteotomies, Tumor Surgery, Trauma, and Surgical Training and Education. Quality assessment could be performed in 18 studies. Among the clinical studies, there were six case series with an average score of 90% and one case report, which scored 81% according to the Joanna Briggs Institute Critical Appraisal Checklist (JBI CAC). The 11 cadaveric studies scored 81% according to the QUACS scale (Quality Appraisal for Cadaveric Studies). Conclusion: This manuscript provides 1) a summary of the current state of knowledge and research of Augmented Reality in orthopedic surgery presented in the literature, and 2) a discussion by the authors presenting the key remarks required for seamless integration of Augmented Reality in the future surgical practice. Trial registration: PROSPERO registration number: CRD42019128569.

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Purpose: High tibial osteotomy (HTO) is an effective treatment option in early osteoarthritis. However, preoperative planning and surgical execution can be challenging. Computer assisted three-dimensional (3D) planning and patient-specific instruments (PSI) might be helpful tools in achieving successful outcomes. Goal of this study was to assess the accuracy of HTO using PSI. Methods: All medial open wedge PSI-HTO between 2014 and 2016 were reviewed. Using pre-and postoperative radiographs, hip-knee-ankle angle (HKA) and posterior tibial slope (PTS) were determined two-dimensionally (2D) to calculate 2D accuracy. Using postoperative CT-data, 3D surface models of the tibias were reconstructed and superimposed with the planning to calculate 3D accuracy. Results: Twenty-three patients could be included. A mean correction of HKA of 9.7°± 2.6°was planned. Postoperative assessment of HKA correction showed a mean correction of 8.9°± 3.2°, resulting in a 2D accuracy for HKA correction of 0.8°± 1.5°. The postoperative PTS changed by 1.7°± 2.2°. 3D accuracy showed average 3D rotational differences of − 0.1°± 2.3°in coronal plane, − 0.2°± 2.3°in transversal plane, and 1.3°± 2.1°in sagittal plane, whereby 3D translational differences were calculated as 0.1 mm ± 1.3 mm in coronal plane, − 0.1 ± 0.6 mm in transversal plane, and − 0.1 ± 0.6 mm in sagittal plane. Conclusion: The use of PSI in HTO results in accurate correction of mechanical leg axis. In contrast to the known problem of unintended PTS changes in conventional HTO, just slight changes of PTS could be observed using PSI. The use of PSI in HTO might be preferable to obtain desired correction of HKA and to maintain PTS.

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