During recent years, research has, provided evidence that increasing interorganizational collaborations (networking) play a central role in determining firms innovation by demonstrating that the locus of innovation is an interorganizational system of actors.Both the relationship between networking and innovation and the role of science partners in interorganizational relationships and R&D networking have been given a great deal of attention. The interest is stimulated by the contribution to economic development, competitive advantage creation, firms performance, expecially in high-tech industry.The main purpose of this study is to explore the dynamic of the relationship between networking and innovation and science parks' role in providing the linkages to all firms and agents in interorganizational system of innovation.The empirical evidence of the paper consists of a survey of 15 Italian Science Parks and show networking process facilitate the innovation projects but it will not necessarily lead to innovation success.
Purpose
– The purpose of this paper is to present some evidence on the role of management models in the implementation or in the transformation of the business models, highlighting the pivotal role of managerial dynamic capabilities. The analysis provides relevant lines of managerial action both strategic and operational levels.
Design/methodology/approach
– An innovative conceptual analysis is proposed. Managerial dynamic capabilities play a central role in the coupled link between management model and business model at the organizational level.
Findings
– The authors propose a highly usable and generalizable conceptual model for management practices, strategic planning and operational assessment.
Originality/value
– This paper investigates a new emerging research stream of management innovation theory. The research presents a new and innovative conceptual analysis of management model and business model alignment. This theme has not been explored in prior researches and represents an experiment to pair the management model and the business model evidence.
Objective
To investigate the clinical characteristics, the neuroimaging features and associated anomalies observed in children affected by Dandy–Walker malformations (DWM) and variants (DWV) in a single tertiary hospital in Catania and compare our data to their existent in the literature.
Methods
A retrospective case series using the medical records has been performed on 28 children diagnosed with DWM and DWV admitted to a single tertiary section of Pediatric Neurology, Department of Catania, Italy from January 2005 to January 2021. We reviewed the neuroimaging using the new diagnostic criteria of Klein et al.
Results
Associated anomalies were frequently reported. Among these, hydrocephalus was found in 13/28 (48%), and hydrocephalus plus corpus callosum anomalies in three children (10%). We described corpus callosum, cardiac and genitourinary anomalies in 2/28 (7%), 3/28 (10%), and 3/28 (10%), respectively. The most common clinical features were the developmental delay and epilepsy observed in 19/28 (67%) and in 9/28 (32%) of the cases. The first exam at the diagnosis was MRI in 17/28 patients, followed by transfontanellar ultrasound in 5/28, computed tomography in 4/28 and prenatal ultrasound in 2/28. To note, a child with DWM was affected by Down syndrome and one by congenital disorders of N-linked glycosylation (CDG-IId).
Conclusions
Children with DWV were more commonly observed than children with DWM. Hydrocephalus is an anomaly, frequently and equally reported in both DWM and DMV. Perinatal complications were frequent adverse events with severe respiratory distress and need for cardiopulmonary resuscitation. Cognitive involvement and epilepsy were the most common comorbidities. Single DWV is associated with a better developmental outcome.
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