The purpose of this study was to compare the feto-maternal outcome after induction of labor in oligohydramnios and borderline liquorat term. STUDY DESIGN: This retrospective study was conducted in a medical college and general hospital with women of 37-42 weeks' gestation. The amniotic fluid index (AFI) was determined in all cases using the four-quadrant technique. The cases were divided into two groups based on their AFI. Oligohydramnios group (n=102) with AFI ≤ 5 cm and borderline liquor group (n=99) with AFI of 5.1 to 8 cm. Induction of labor was done by misoprostol in all cases. Different maternal outcomes like mode of delivery, indication for operative or instrumental delivery, meconium stained liquor and perinatal outcomes were compared in between the two groups.RESULTS: The two groups were similar with regard to maternal age, parity, and gestational age. Meconium staining of the amniotic fluid was significantly higher in the group with AFI < 5 cm (p = 0.05). The number of cesarean deliveries and incidence non-reassuring fetal heart (fetal distress) were similar in both the groups. There was no significant difference between the two groups with regard to Apgar scores or admission to neonatal intensive care unit (NICU). CONCLUSION: Induction of labor at term in women with oligohydramnios is associated with an increased incidence of meconium staining of the amniotic fluid but the risk of cesarean delivery or fetal distress it is not increased as compared with borderline liquor.

A 40-year-old G 2 P 1 L 1 female with previous LSCS (Lower Segment Cesarian Section) with secondary subfertility conceived following frozen embryo replacement. Trans Vaginal Ultrasonography (TVS) at eight weeks suggested gestational sac measuring 25mm × 15mm with surrounding chorionic tissue, extending into cervical isthmic junction at the scar anteriorly [ Cases of Caesarean Scar Ectopic Pregnancy (CSEP) are becoming increasingly common at tertiary care hospitals because of increase in rate of CS. This condition is often complicated by life threatening bleeding, uterine rupture, which might require hysterectomy leading to permanent infertility. Management can be medical, surgical or combined depending on the clinical presentation. It includes systemic methotrexate or local uterine artery chemoembolisation, dilatation and curettage, excision of trophoblastic tissue either by laparoscopy or laparotomy with uterine repair. We report two such cases managed medically in our hospital. Both the cases presented to us were asymptomatic except amenorrhoea and were diagnosed by transvaginal sonography. First case was managed with systemic methotrexate followed by Dilatation and Curettage (D&C). Second case was managed with systemic methotrexate alone successfully.

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Background: Purpose of this study was to evaluate the in vitro fertilisation outcome in patients having normal or elevated day-2 serum progesterone level undergone IVF by using GnRH antagonist.Methods: A retrospective study conducted in Institute of Reproductive Medicine, Chennai during January 2013 to March 2014. According to patient’s Day-2 serum progesterone level the total no of cases (N=151) were divided into two groups group-1 (N=116) with progesterone value ≤1.5ng/ml and group-2 (N=35) with progesterone value>1.5ng/ml. Ovarian stimulation was started with recombinant FSH on day 2 and GnRH antagonist injections started from day 6 of stimulation. Total dose of gonadotropins, days of gonadotrophin injections, no of eggs collected, Clinical pregnancy rate and live birth rate were compared between two groups.Results: Two groups were similar with regards to age, BMI, days of gonadotrophins and total doses of gonadotrophins. Incidence of elevated P level was 23.17%. Total pregnancy rate was 36.42%. A non-statistically-significant difference was observed in clinical pregnancy (37.06% vs 34.28%) and live birth (32.75% vs 28.57%) between the normal and elevated progesterone groups.Conclusions: Elevated day-2 serum progesterone level   was associated with lower clinical pregnancy rate but it was not statistically-significant.