The aim of this study was to evaluate the effectiveness of a pharmaceutical grade isoflavone supplement (Inoclim ® ) 40 mg per capsule of soy extract rich in daidzin and genistin) on the number of hot flashes and night sweats in menopausal African women. This open, prospective, multicenter study involved 140 menopausal women with climacteric symptoms (i.e., a minimum of five hot flashes and/or moderate to severe night sweats per day). These patients received a daily 40-mg supplement of soy isoflavone contained in an Inoclim ® capsule (Laboratoire Innotech International, France). The dose was increased to two capsules per day when there were more than five hot flashes or when the women could not sleep because of night sweats. The patients were followed up over a 4-month period and data were analyzed using EPI-Info TM version 3.5.1. The outcome measure was fewer hot flashes and night sweats. The mean daily number of episodes of hot flashes was 5.7 at baseline and 1.8 at week 16, corresponding to a decrease of 68.4% (n = 93 patients at baseline and n = 66 at 16 weeks). The mean number of daily episodes of night sweats was 3.7 at baseline and 0.8 at week 16, corresponding to a decrease of 78.4% (n = 127 patients in the first week and n = 73 at 16 weeks). Over 80% of patients took a single one 40 mg capsule per day. The percentage of patients who adhered to the prescription was more than 95% during the 4-month follow-up period. These results confirm the effectiveness of a pharmaceutical grade isoflavone supplement (40 mg, rich in genistin and daidzin) on vasomotor symptoms in menopausal women.
Severe damage to the right rectus abdominus muscle associated with a uterine broad right ligament hematoma is rare complications of an accident during pregnancy. We report the case of a 31 years old primiparous pregnant woman, who had been victim of a road accident at 28 weeks of pregnancy, when as a pediatrian she was hit by a car. The site of impact was in the right anterolateral area on the abdomen. The pregnancy continued normally and she was ultimately delivered vaginally at 41 weeks of gestation. The baby was normally grown and had Apgar scores of 9 and 10 at 1 and 5 minutes of life. She underwent a laparotomy in the immediate postpartum period for a significant hemoperitoneum; this revealed the lesions and allowed treatment. The postoperative course was uneventful and the patient was discharged on the 6th post-partum day.
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