validity of current animal studies, high quality experimental studies and efforts for effective translation from preclinical studies to clinical trials are still required. The present study also demonstrates that moderate confidence could be placed in safety of MSCs therapy for knee OA but with low confidence in efficacy outcomes due to limitations of the current evidence. Further high-quality studies with high internal and external validity are still required.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.