ABSTRACT--Susceptibilities of spangled emperor Lethrinus nebulosus, estuary cod Epinephelus malabaricus and cobia Rachycentron canadum cultured in subtropical Japan to red sea bream iridovirus (RSIV) were studied by experimental infections. Estuary cod showed as high susceptibility to RSIV as red sea bream Pagrus major. In contrast, the susceptibilities of spangled emperor and cobia to the virus were compara tively low. The result corresponds with the occurrence of the disease in the net cages.
The
presented work describes the synthesis and characterization
of a novel magnetic cationic phospholipid (MCP) system with a stable
dopamine anchor as well as its transfection activity study. The synthesized
architectural system increases the biocompatibility of iron oxide
and promises applications of magnetic nanoparticles in living cells.
The MCP system is soluble in organic solvents and can be easily adapted
to prepare magnetic liposomes. We created complexes with liposomes
containing MCP and other functional cationic lipids and pDNA as gene
delivery tools, which possessed the ability to enhance the efficiency
of transfection, particularly the process of interaction with cells
by inducing a magnetic field. The MCP is able to create iron oxide
nanoparticles and has the potential for the materials to prepare the
system for site-specific gene delivery with the application of an
external magnetic field.
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