To the best of our knowledge, this study is the first which shows that anaerobic bacteria were identified in patients' oral flora before and after HSCT by using a mass spectrometer. These results indicate that Enterococcus species and Candida species may have been associated with OM. OM affected the patients' improvement in nutritional status and their prognosis. We concluded that it is important to provide more complete oral care instructions and interventions to prevent these bacterial infections.
In April 2012, the Center of Special Needs Dentistry SND was established at Showa University Dental Hospital to provide function training for children with eating and swallowing disorders. A statistical clinical assessment was performed on new patients ≤ 18 years of age who visited the Center over a 1-year period April 2012-March 2013 to assess the conditions present at the initial visit. In all, 60 patients 29 boys, 31 girls, mean SD age 4.2 4.1 years, range 0-18 years of age were included in the study. Most patients were 1 year of age 32 and most came from one of four cities in the Johnan area Shinagawa City, Meguro City, Ota City and Setagaya City. The most common primary diseases at the initial visit were cerebral palsy and cleft lip and palate. The third largest patient group was of healthy children with oral function problem. Over 60 of patients attended the Center of SND because of an eating-related complaint. More than 50 of patients were obtaining nutrients via oral intake ; the remaining patients were obtaining nutrients via non-oral or a combination of oral and nonoral intake. Because of the young age of the patients and the fact that most were from neighboring areas, it can be inferred that effective community health care is being provided. It is necessary for the Center of SND to continue to provide professional treatment for dysphagia and to contribute to community medicine.
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