Faloak (Sterculia quadrifida R.Br., Sterculiaceae) is an Indonesia indigenous plant widely used as a traditional remedy for various health complaints. This study aimed to explore the immunomodulatory and cytotoxicity potentials of Faloak bark by using in vitro techniques. Barks was extracted using water, ethanol and ethanol: water (1:1) separately. Colorimetric analysis was used for the determination of the total phenolic and the total flavonoid contents. Immunomodulator activities of the extracts were evaluated by studying their effects on mice macrophages and lymphocytes using in vitro methods, while the cytotoxicity potential was evaluated against Vero and HepG2 cell lines. The active extract was further fractionated and tested using different cell lines by the MTT method. Data were analyzed using one-way ANOVA and LSD tests, with a 95% confidence level (p<0.05). All extracts significantly increased the phagocytosis of macrophages compared to that of control in a concentrationdependent manner. However, all the extracts exhibited the Stimulation Index value of < 2, which indicated no effect on lymphocyte proliferation. The ethyl acetate fraction showed the highest activity against T47D, MCF7 and HepG2 cells with IC50 9.56; 7.62; 3.24 µg/mL and the Selectivity Index (against Vero cells) as follows, 2.01; 2.52; 5.94, respectively. Faloak bark extracts can stimulate macrophage phagocytosis activity in vitro, which positively correlates to the contents of flavonoids and other phenolic compounds. The ethyl acetate fraction exhibited the highest activity, which supports its potency as cancer chemopreventive herbal medicine.
Perkembangan internet yang semakin pesat menyebabkan perubahan perilaku konsumen dalam membeliproduk. Salah satu dari efek tersebut adalah tuntutan konsumen dalam layanan pemasaran dalamjaringan (daring) atau online yang dilakukan melalui media internet. Kelebihan penggunaan internetdalam kegiatan jual beli atau bisnis adalah mudah, cepat, dan dapat diakses kapan saja dan dimanasaja tanpa terikat ruang dan waktu. Model pemasaran dengan menggunakan internet atau onlinediprediksi akan menjadi sebuah nilai tambah bagi produk atau jasa di masa mendatang.Tujuan utamadari program hibah pengabdian Program Kemitraan Masyarakat (PKM) Lembaga Penelitian, Publikasi,dan Pengabdian UMY ini adalah untuk meningkatkan kemampuan dari khalayak dusun mitra, yaitupengrajin anyaman bambu di Dusun Tangkil Desa Muntuk Dlingo Kabupaten Bantul DaerahIstimewa Yogyakarta, dalam memasarkan produk secara online. Mitra secara teknis diajarkanbagaimana cara membuat katalog yang menarik, mendaftarkan profil bisnis di mesin pencari googleserta toko-toko online yang ada di Indonesia. Selain itu, mitra juga diajarkan bagaimana cara beriklansecara online. Hal ini diharapkan akan meningkatan pendapatan masyarakat desa mitra. Upaya yangdilakukan untuk mencapai tujuan tersebut antara lain adalah penyuluhan mengenai pemasaran daring(online marketing), pelatihan dan praktek pembuatan katalog, mendaftarkan produk atau jasa yangditawarkan ke mesin pencari google dan toko online, serta penyuluhan mengenai model pemasaransecara online. Program hibah kemitraan PKM oleh LP3M UMY ini pada akhirnya dapat membantumeningkatkan kemampuan masyarakat desa mitra dalam bidang pemasaran secara online, mulai daripembuatan katalog yang menarik hingga cara melakukan promosi melalui internet atau online, sehinggadapat bersaing dengan kompetitor-kompetitor yang sudah ada.
Public understanding of the use of drugs that are not true can cause new health problems. This empowerment activity aims to increase people's understanding on medicine. This activity was conducted at SD Muhammadiyah Demangan Yogyakarta. The activities were conducted in stages, including joint program planning, tutorials (lectures), practice of recognizing and understanding medicine, mentoring, and recitation on understanding medicine. The main topic of discussion is knowledge about medicine, then added knowledge about healthy snacks, vitamins and their benefits for the body, as well as the role of the pharmacist profession in pharmaceutical services. The results of this service show an increase in the understanding of elementary school students about the use of drugs, healthy snacks, vitamins and their functions for the body as well as knowledge related to the pharmacist profession. There were 26 students of the 30 students who participated in the drug use assistance whose posttest scores improved compared to the pretest scores.
ABSTRAKSistem Informasi Kesehatan (SIMKes) merupakan bagian penting dari sistem kesehatan suatu negara. SIMKes adalah bentuk utama Sistem Kesehatan Nasional (SKN) yang digunakan sebagai komponen dalam pembangunan berwawasan kesehatan. Sistem informasi yang tersusun dan terkonsep akan menghasilkan luaran yang baik dan membuat masyarakat tidak buta dengan dunia kesehatan. Teknologi informasi berkembang secara cepat dan berdampak pada semua aspek kehidupan, termasuk informasi kesehatan. Perkembangan teknologi saat ini berperan penting menjadi sebuah media bagi masyarakat milenial atau tenaga kesehatan untuk mendapatkan informasi mengenai gambaran kesehatan dan persebaran penyakit atau epidemiologi di wilayahnya masing-masing. Program Hibah Kemitraan ini bertujuan untuk melatih para kader kesehatan di setiap Padukuhan di Desa Tijayan Manisrenggo Jawa Tengah bagaimana cara membuat profil kesehatan dan peta persebaran penyakit di desa tersebut dan menyajikannya secara interaktif, edukatif, dan berbasis elektronik. Sasaran utama dalam program ini adalah kader kesehatan masingmasing padukuhan yang terdapat di Desa Tijayan, meliputi Bawangan, Candran, Pogaten, dan Sorobayan. Beberapa program kegiatan untuk mencapai tujuan tersebut meliputi pengumpulan data kesehatan yang didapat melalui survey atau sensus dan data yang sudah tersedia di pusat data kesehatan desa, penyuluhan tata cara pembuatan profil kesehatan dan peta persebaran penyakit, dan pelatihan penyajian data informasi kesehatan masyarakat secara interaktif dan edukatif. Program Hibah Kemitraan ini dapat membantu melengkapi profil kesehatan masyarakat dan meningkatkan kualitas SIMKes di desa mitra.Kata kunci: profil kesehatan; sistem informasi kesehatan; sisten kesehatan nasional. ABSTRACT Health Information System (HIS) is an important component of a country's health system.HIS is the main part of the National Health System, which is used as a pillar in health-oriented development. The structured and conceptual information system produces good outcomes and prevents people from the blindness of health matters. Information technology develops rapidly and impacts most of all aspects of life, including health information. Current technological developments play an important role as a media for millennial people or health professionals to get information about health information and epidemiology in their own region. This program aimed to train health cadres in each region of the Tijayan Manisrenggo Village, Klaten, Central Java, in addition to creating an electronic health profile and epidemiology map of the village and then presenting the profile interactively and educatively. The main targets of this program were health cadres in each region of the Tijayan Village, including Bawangan, Candran, Pogaten, and Sorobayan. Some main activities to achieve the objectives included collecting health data obtained through surveys or censuses and data already available in the health data center of the village, counseling procedures for creating an electronic health profile and...
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