Overall incidence of neonatal seizures was 11.7/1000 live births, majority being preterm very low birth weight babies before 5 days of life. Perinatal asphyxia was responsible in 44.44% babies followed by metabolic abnormalities (23.33%). EEG abnormalities were present in 33.34% babies.

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Objective: To evaluate the adequacy and feasibility of spoon feeding in terms of physical growth and transition to breast feeding in early hospitaldischarged low birth weight (LBW) neonates.Study Design: A trial with two independent randomized controlled trials (RCTs), which was conducted at the tertiary-level neonatal unit of a teaching hospital and included home-based treatment. Singleton liveborn neonates with a gestational age of X32 weeks, a birth weight of >1250 g and p1600 g, and fulfilling the feeding criteria were included in the study. The study was conducted over an 18-month period with 79 and 65 subjects enrolled into two RCTs in a large trial. Weight gain pattern during the study period was the primary outcome variable, and the number of days required by the neonate for transition to breast feeding and feeding-associated morbidity were the secondary variables. In Trial I, babies were gradually transitioned from nasogastric (NG) feeding and spoon feeding to breast feeding in the hospital, whereas in Trial II, babies were transitioned from spoon feeding to breast feeding in the hospital and at home. Eligible neonates were randomized into one of the two groups in each of the two trials using a computer-generated random number sequence. Trial I consisted of NG feeding and spoon feeding groups, both in a hospital setup, whereas Trial II consisted of a spoon-feeding group in hospital and home setups.Result: Baseline neonatal and maternal characteristics were comparable in both groups of each trial, including maternal medical and obstetrical morbidities. In Trial I, out of 79 babies enrolled, 72 babies (91.1%) completed the study, whereas in Trial II, 92.3% (60 babies out of 65 babies enrolled) neonates completed the trial. The mean (s.d.) weight gain in neonates during the study period in Trial I in a hospital setup was 4.72 (4.68) g kg À1 per day in the NG feeding group and 4.47 (3.14) g kg À1 per day in the spoon-feeding group (P ¼ 0.8836).

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