Purpose In this study, we aimed to determine the regenerative and antimicrobial impact of the electrospun nanofiber mats, with/without silver nanoparticles (AgNPs), on full-thickness skin wounds in rabbits. Methods Polyvinyl alcohol was combined with gelatin to provide biocompatible electrospun binary nanofiber mats. AgNPs were added to the polyvinyl alcohol/gelatin mixture to obtain ternary nanofiber-AgNPs mats. Binary and ternary nanofiber mats were characterized by scanning electron microscopy before being applied as wound dressings in vivo. Subsequently, wound healing was evaluated. Results Both nanofiber/nanofiber-AgNPs mats improved the microscopic quality of the healed skin, albeit without obvious acceleration of the healing rate. As well, both types of nanofiber mats were able to combat microbial invasion into the wound bed. Conclusions Both binary polyvinyl alcohol/gelatin and ternary polyvinyl alcohol/gelatin/AgNPs nanofiber mats developed in the present study depicted similar regenerative and antimicrobial potential when applied as full-thickness wound dressing. However, in comparison to the binary nanofiber mats, no obvious synergistic effect was observed after loading nanofibers with AgNPs.

In this study polypropylene mesh was used to facilitate reconstruction of large tissue defects by tension-free repair in 5 crossbred calves with hernial ring sizes ranging from 4-9 cm. The mesh was anchored subcutaneously to strong supportive musculature with interrupted pattern using No. 3 polypropylene sutures. The results revealed that polypropylene mesh proved alternative for hernial repair when fixed subcutaneous in large hernial ring in male and female calves without complications. Therefore, prosthetic mesh represents a safely procedure in large hernial ring to avoid over-stretching on the edges of the wound which hinders wound healing.

A survey study was done during the period between September 2010 and December 2012 on 2580 Friesian cows and heifers distributed in four armed forces farms.This work revealed that, teat wounds represent the higher acquired teat affections (28.16 %) while teat papilloma represents the lowest affection (1.65 %). The supernumerary teat represents the higher congenital teat abnormalities (36.8 %) while the lower was incompetent teat (1.5 %).The present study revealed that the prevalence of acquired teat affections were in November, December, January, and February, whenever the weather is cold and rainy and stables are muddy and the accidental injuries during milking, feeding or even laying were predominant and predictable.

No abstract

Key words: