Objectives: the aim of this study was to determine the impact of cardiac injury on clinical profile, cardiac evaluation and outcome in patients hospitalized with convulsive status epilepticus (CSE). Materials and methods: this prospective observational study included 74 children with CSE. Cardiac injury was evaluated and defined using combination of cardiac troponin, electrocardiography (ECG) and echocardiography. Clinical outcome and mortality rates were compared in patients with and without cardiac injury. Results: A total of 74 patients with CSE were included in the study. Thirty-six (48.6%) patients demonstrated markers of cardiac injury. ECG changes occurred in 45.9% and echocardiographic signs of left ventricular systolic and diastolic dysfunction reported in 5.4% and 8.1%, respectively. The mean length of hospital stays and need for ICU admission were significantly higher in patients with cardiac injury compared to others. One third of patients with cardiac injury needed mechanical ventilation and this was significantly higher than patients without (p = 0.042). hypotension and/or shock developed in 25% of cardiac injury patients and most of them required inotropic support; this was significantly higher than others without markers of cardiac injury. The overall mortality in cardiac injury group was higher (13.9% vs. 2.6%); however, this difference was not statistically significant. Conclusion: Markers of cardiac injury were common and associated with poor clinical outcome and higher risk of mortality in patients with CSE, so extensive routine cardiovascular evaluation is essential in these patients.
Objective: This study is designed to assess the accuracy of Body Mass Index, waist circumference, waist Hip Ratio or Waist Height Ratio as a predictor of ovarian response in women undergoing ICSI. Patients and Methods: This Pilot study was done at Clinical IVF and ART unit at Faculty of Medicine, Ain-Shams University Hospital, Number of Participant women 150. Results and Conclusion:The anthropometric measures, only the waist circumference, waist/hip ratio and waist/height ratio were related to ovarian response (p-value = 0.014, 0.004 and 0.020, respectively) and to the occurrence of clinical pregnancy (p-value = 0.017, 0.030 and 0.010, respectively). The measures, however, were modest predictors for either outcome. A waist circumference ≤ 0.81 cm could predict good ovarian response with a sensitivity of 35% and specificity of 100% (AUC = 0.656) and a waist circumference >98 cm could predict clinical pregnancy with a sensitivity of 61% and specificity of 80% (AUC = 0.609). A waist/hip ratio ≤0.82 could predict good ovarian response with a sensitivity of 62.4% and specificity of 68% (AUC = 0.652) and a ratio >0.84 could predict clinical pregnancy with a sensitivity of 56.3% and specificity of 70.9% (AUC = 0.612).On the other hand, a waist/height ratio ≤0.54 could predict good ovarian response with a sensitivity of 48% and specificity of 92% (AUC = 0.651), while a waist/height ratio >0.62 cm could predict clinical pregnancy with a sensitivity of 61% and specificity of 80% (AUC = 0.609).
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