Disease diagnosis based on retinal image analysis is very popular in order to detect a few critical diseases such as diabetic retinopathy, high blood pressure, cancer and glaucoma. The important part in the retinal is a blood vessel. Besides, the blood vessel study plays an important part in different medical areas such as ophthalmology, oncology, and neurosurgery. The significance of the vessel analysis was helped by the continuous overview in clinical studies of new medical technologies intended for improving the visualization of vessels. In this paper, a new blood vessel detection based on a combination of Kirsch’s templates and Fuzzy C-Means (FCM) was proposed. The main objective of this study is to improve the detection result of FCM and achieved more effective performance compared to the Kirsch’s templates result. The proposed method experimented on 20 images is utilized namely from Digital Retina Images for Vessel Extraction (DRIVE) dataset. The resulting images are compared with the benchmark images based on a few image quality assessment (IQA) such as accuracy, sensitivity and specificity. The total average of accuracy is 92.64%, while sensitivity and specificity got 95.73% and 60.45% respectively.
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