o evaluate the changes in PIH (Pregnancy Induced Hypertension) by using haematologicaland coagulation parameters like platelet count, MPV, PDW, PT and APTT. Materials and methods: Atotal of 150 cases comprising 75 control groups and 75 cases group (pregnancy-inducedhypertension) were enrolled in the study. Hematological parameters like platelet count, MPV, PDWand coagulation parameters like PT and APTT were studied in these patients. Data entry was done inan excel spreadsheet and by using SPSS (version -20). Results: The hematological parameter -Platelet count was markedly reduced in patients with preeclampsia compared to normal pregnantpatients. MPV, PDW, PT and APTT were increased which is statistically significant. Conclusion: Theabnormalities about hematological and coagulation parameters in preeclampsia are the prognosticmarkers used as an additional diagnostic criterion for preeclampsia in rural hospitals.
Heparin-induced thrombocytopenia (HIT) is a less commonly encountered adverse reaction of heparin characterized by formation of heparin complex with platelet factor 4 due to formation of autoantibody. HIT is reported in about 2% of all patients receiving heparin, out of which 35% develop thrombosis. In Antiphospholoipid syndrome autoantibodies are generated to phospholipid binding proteins which are risk factors for thrombosis and pregnancy complications. In this report we present case of a patient with recurrent venous thromboembolism receiving heparin and was found to develop HIT with coexistence of Antiphospholipid syndrome.
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