Heart failure is still one of the public health concerns with high morbidity and mortality rate, especially in developed as well as developing countries, including Indonesia. In heart failure with hypertension there will be diastolic or systolic dysfunction of left ventricle that is closely related with heart failure incidents. This study was aimed to obtain the profile of patients with heart failure associated withn hypertension that were admitted to Prof. Dr. R. D. Kandou Hospital Manado from September to Desember 2016. This was a descriptive prospective study with a cross sectional design. The results showed that of the total 167 heart failure patients, it was found that 70 patients (41.9%) had hypertension. Males (65.7%) were more commonly than females (34.3%). Based on the echocardiography examination, diastolic heart failure was the most common which accounted for 38 patients (54.9%), meanwhile 19 patients had systolic heart failure (27.2%), and 13 patients had the combination of systolic and diastolic heart failure (18.5%). Conclusion: In patients with heart failure associated with hypertension, diastolic heart failure in the form of relaxation disturbance was the most commonly found.Keywords: description, heart failure, hypertension Abstrak: Gagal jantung masih merupakan suatu masalah kesehatan masyarakat dengan angka morbiditas dan mortalitas yang tinggi baik di negara maju maupun di negara sedang berkembang termasuk Indonesia. Pada gagal jantung dengan hipertensi akan ditemukan disfungsi diastolik atau sistolik dari ventrikel kiri yang berhubungan erat dengan peningkatan insiden gagal jantung. Penelitian ini bertujuan untuk mendapatkan gambaran pasien gagal jantung disertai hipertensi yang menjalani rawat inap di RSUP Prof. Dr. R. D. Kandou Manado periode September – Desember 2016. Jenis penelitian ialah deskriptif prospektif dengan desain potong lintang. Hasil penelitian mendapatkan dari total 167 pasien gagal jantung, ditemukan gagal jantung disertai hipertensi sebanyak 70 pasien (41,9%). Berdasarkan hasil pemeriksaan ekokardiografi didapatkan klasifikasi terbanyak ialah gagal jantung diastolik sebanyak 38 pasien (54,3%), gagal jantung sistolik sebanyak 19 pasien (27,2%), dan kombinasi gagal jantung sistolik diastolik sebanyak 13 pasien (18,5%). Prevalensi terbanyak terdapat pada laki-laki (65,7%). Simpulan: Pada pasien gagal jantung dengan hipertensi yang tersering ditemukan ialah gagal jantung diastolik ventrikel kiri, berupa gangguan relaksasi.Kata kunci: gambaran, gagal jantung, hipertensi
From year to year, heart disease cases show an increase as the leading cause of death in the world. Acute coronary syndrome (ACS) is a set of manifestations or symptoms caused by a disturbance in the coronary artery. Blood cholesterol level is one of the major risk factors underlying ACS. High total cholesterol and low high density lipoprotein (HDL) levels will increase the ratio of both and are directly related to increased coronary heart disease. The ratio can be obtained by dividing total cholesterol level with HDL level. This study was aimed to obtain the correlation between ratio of total cholesterol to (HDL) with the incidence of ACS at Prof. Dr. R. D. Kandou Hospital Manado. This was a descriptive analytical study with a retrospective cross sectional design using medical record data. Data were analyzed by using the chi-square test. There were 117 patients obtained by using total sampling technique. The chi-square test showed a P value of 0.026 (P <0,05). Conclusion: There was a significant correlation between the ratio of total cholesterol to HDL and the incidence of ACS.Keywords: acute coronary syndrome, ratio of total cholesterol to HDL. Abstrak: Kasus penyakit jantung dari tahun ke tahun menunjukkan adanya peningkatan sebagai penyebab kematian tertinggi di dunia. Sindrom koroner akut (SKA) merupakan sekumpulan manifestasi atau gejala akibat gangguan pada arteri koronaria. Kadar kolesterol darah merupakan faktor risiko utama proses aterosklerosis yang mendasari terjadinya sindrom koroner akut. Kadar kolesterol total yang tinggi dan HDL yang rendah akan meningkatkan rasio dari keduanya dan berhubungan langsung dengan peningkatan risiko penyakit jantung koroner. Rasio dapat diperoleh dengan cara membagi kadar kolesterol total dengan HDL. Penelitian ini bertujuan untuk mengetahui hubungan antara rasio kadar kolestrol total terhadap high density lipoprotein (HDL) dengan kejadian SKA di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah deskriptif analitik dengan desain potong lintang dan retrospektif menggunakan data rekam medis pasien. Data dianalisis dengan uji chi-square. Jumlah sampel penelitian sebanyak 117 pasien diperoleh dengan teknik total sampling. Hasil uji chi-square menunjukkan nilai P=0,026 (P <0,05). Simpulan: Terdapat hubungan bermakna antara rasio kadar kolesterol total terhadap HDL dengan kejadian SKA.Kata kunci: rasio kadar kolesterol total terhadap HDL, sindrom koroner akut
The functional status of patients with chronic heart failure (CHF) has been standardized by the classification of NYHA [New York Heart Association] class I-IV. One of the parameters to assess the ability of the heart function is the ejection fraction (LVEF) were assessed using echocardiography parameters. The purpose of this study was to determine the relationship of NYHA class with ejection fraction in patients with chronic heart failure in the BLU/Prof. Dr. R. D. Kandou Manado. Methodology: This research method is analytic cross sectional study approach. The sample was CHF patients in BLU/Prof. Dr. R. D. Manado Kandou 30 people held during November-December 2012. Results: The distribution of patients according to NYHA class most are in NYHA II (43%), while the lowest are in NYHA IV (7%). Distribution according to the ejection fraction is at most 30-39% LVEF is 12 and there are at least LVEF <30%, is 6 people. The results obtained using the Spearman test (p = 0.177), indicating that there was no statistically significant association between NYHA class with ejection fraction in patients with chronic heart failure in the BLU/Prof. Dr. R. D. Kandou Manado.Conclusion: No significant relationship was found between NYHA class with ejection fraction. Keywords: Chronic Heart Failure, ejection fraction, NYHA class Abstrak: Status fungsional penderita gagal jantung kronik (GJK) ini telah dibakukan berdasarkan klasifikasi NYHA [New York Heart Association] kelas I-IV. Salah satu parameter untuk menilai kemampuan fungsi jantung adalah fraksi ejeksi (LVEF) yang dinilai menggunakan parameter ekokardiografi. Tujuan penelitian ini adalah untuk mengetahui hubungan kelas NYHA dengan fraksi ejeksi pada penderita gagal jantung kronik di BLU/RSUP Prof. Dr. R. D. Kandou Manado. Metodologi: Metode penelitian ini bersifat analitik dengan pendekatan studi cross sectional. Sampel penelitian ini adalah pasien GJK di BLU/RSUP. Prof. Dr. R. D. Kandou Manado sebanyak 30 orang yang berlangsung selama bulan November – Desember 2012. Hasil : Distribusi pasien GJK menurut kelas NYHA terbanyak berada pada NYHA II (43%), sedangkan yang paling rendah berada pada NYHA IV (7%). Distribusi menurut Fraksi Ejeksi terbanyak berada pada LVEF 30-39 % yaitu 12 orang dan paling rendah terdapat pada LVEF <30 % yaitu 6 orang. Hasil penelitian ini menggunakan uji Spearman diperoleh (p= 0,177), menunjukkan bahwa secara statistik tidak terdapat hubungan bermakna antara NYHA kelas dengan fraksi ejeksi pada pasien gagal jantung kronik di BLU/RSUP Prof. Dr. R. D. Kandou Manado. Kesimpulan:Tidak ditemukan hubungan yang signifikan antara kelas NYHA dengan fraksi ejeksi. Kata kunci : Fraksi ejeksI, Gagal Jantung Kronik, Kelas NYHA [New York Heart Association]
Coronary heart disease (CHD) is the leading cause of death in the world and marked by the existence of atherosclerotic plaque at the coronary artery that progressively blocks the blood stream to myocardium resulting in myocardial infarction. Elevated of leukocyte count typically indicates an infection or inflammation, and has a role in vascular injury and atherogenesis that is a development of an atherosclerotic ruptured plaque and trombosis. This study was aimed to obtain the profile of leukocyte count in patient with acute myocardial infarction (AMI) at Prof. Dr. R. D. Kandou Hospital Manado from January to December 2015. This was an observational descriptive study with a retrospective approach using data of medical records of AMI patients who came to Prof. Dr. R. D. Kandou Hospital Manado from January to Desember 2015. The results showed that of totally 63 medical records of patients with AMI, there were 45 samples that fulfilled the inclusion criteria. The majority patients were in the age group 46-60 years, males, the risk factor was a combination of several major risks, and NSTEMI as the type of type of infarction. There were 57,77% of leukocyte count results ranged 10,000-14,900/mm3 and 8,88% were ≥15,000/mm3. Conclusion: There was an increase in the leukocytes count in more than half of the samples. Keywords: acute myocardial infarction, leukocyte, inflammation Abstrak: Penyakit jantung koroner (PJK) merupakan penyebab kematian tersering di dunia dan ditandai adanya plak aterosklerosis pada arteri koroner yang secara progresif menghalangi aliran darah ke miokardium yang berakibat terjadinya infark miokard. Peningkatan jumlah leukosit secara tipikal mengindikasikan adanya suatu infeksi dan peradangan, serta juga berperan pada cedera vaskular dan aterogenesis yang merupakan perkembangan dari suatu ruptur plak aterosklerosis dan trombosis. Penelitian ini bertujuan untuk mengetahui gambaran jumlah leukosit pada pasien IMA di RSUP Prof. Dr. R. D. Kandou periode Januari sampai Desember 2015. Jenis penelitian ialah deskriptif observasional dengan pendekatan retrospektif menggunakan data rekam medik pasien IMA yang berobat di RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Desember 2015 dengan eksklusi riwayat infeksi minimal 2 minggu sebelum masuk rumah sakit. Hasil penelitian mendapatlan 45 sampel dengan mayoritas kelompok usia 46-60 tahun, jenis kelamin laki-laki, faktor risiko kombinasi beberapa faktor risiko mayor, dan jenis infark NSTEMI. Sebanyak 57,77% hasil pemeriksaan leukosit berkisar 10.000-14.900/mm3 dan 8,88% pada ≥15.000/mm3. Simpulan: Lebih dari setengah jumlah sampel mengalami peningkatan jumlah leukosit.Kata kunci: infark miokard akut, leukosit, peradangan
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