Toxoplasmosis is a zoonotic disease that commonly infects goat in Egypt. For its diagnosis, sera form 48 pregnant does were tested for Toxoplasma gondii antibodies through indirect haemagglutination test (IHAT) and modified agglutination test (MAT). Samples were collected between the periods extended from November 2006 to March 2007. The seropositive rate of pregnant does (Meet Kenana, Kalubyia Governorate, Egypt) was 35.42% (17/48). After using MAT test against T. gondii-IgM, 11 sera (22.9%) were found positive. The older animals were more frequently infected (50%) than the younger goats (26.3%). Higher prevalence in aged does was confirmed by MAT. Total T.gondii antibodies and IgM were gradually increased with the development of pregnancy. Two months post treatment with sulfademidine 33.3 %, for 5 successive days at a dose of 200 mg/kg, resulted in not only reduction of T.gondii total antibodies and IgM in all treated does, but re-modulation of T.gondii antibody titres moderately toward the mild titres, and prevention of congenital infection and abortion as well. Whereas IgM was not recorded in treated does, it was detected in the untreated ones. No abortion was recorded in all treated does, but an untreated doe delivered two dead fetuses. The delivered kids belonged to treated does were seropositive for T. gondii antibodies by using IHAT, yet they were seronegative for T.gondii-IgM by using MAT. In contrast, kids belonged to untreated does were seropositive by using both IHAT and MAT. Adequate management might be useful and essential to control toxoplasmosis in the goat herds of Kalubyia Governorate. . 2007. Seroprevalence and preliminary treatment of toxoplasmosis of pregnant goats in Kalubyia Governorate, Egypt.Acta Scientiae Veterinariae. 35: 295-301.
The objective of this research was to clarify the potential impacts of propolis and its nanoparticles in protecting an edible and economically significant tilapian fish, Oreochromis niloticus in Egypt after feeding M. aeruginosa cells mixed with their food on biochemical variables and histopathological changes of liver under laboratory conditions. The results showed that the diet containing M. aeruginosa cells caused aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), creatinine and urea to increase significantly compared to the control groups. Various histopathological modifications were noted in the liver tissues which were described by marked degenerative changes within the hepatic and pancreatic portion. Whereas propolis and nanopropolis co-administration causes these parameters to significantly decrease with best result for nanopropolis. The study concluded that the uptake of M. aeruginosa orally had deleterious impacts on some clinical and biochemical parameters of the blood of Nile tilapia that ultimately impacted the health of fish. The current findings evoked that the administration of propolis and its nanoparticles increases fish health and soothes M. aeruginosa induced toxicity. Nano form of propolis is more efficient in competing toxicity of m. aeruginosa and as hepatoprotective agent.
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