Aim-To determine the number of missed points on frequency doubling technology (FDT) perimetry that optimise the sensitivity and specificity of the test and to determine the topographical accuracy of the test in a clinical setting. Methods-In a prospective study, the perimetric data from 99 patients who underwent both FDT perimetry in the screening mode and Humphrey 24-2 (H24-2) were used to determine the sensitivity and specificity of the FDT perimetry compared with the full threshold H24-2 as the gold standard. Results-Missed points on the FDT perimetry correlated with both the mean deviation and the corrected pattern standard deviation on the Humphrey perimetry. A score assigned to abnormal points on the FDT perimetry and the Humphrey total deviation plot showed a significant correlation for both the location and the depth of the defect. In comparing the Humphrey hemifield test with the FDT perimetry results, if at least one missed point on the frequency doubling test was considered as abnormal then the overall sensitivity of the test was 78.1% and the specificity was 89.1%. Conclusion-FDT perimetry in the screening mode performed in a clinical setting was highly specific, exhibited reasonable sensitivity, and accurately determined the location and depth of scotomas when compared with the full threshold Humphrey 24-2. (Br J Ophthalmol 2001;85:360-362) Frequency doubling technology is a relatively new method of visual field testing that relies on an optical illusion first described by Kelly in 1966.1 The anatomical substrate of this eVect has been ascribed to the retinal ganglion cells (RGCs), 2 which are thought to be particularly susceptible to early glaucomatous damage. This has led to the development of frequency doubling technology (FDT) perimetry with particular use as a glaucoma screening tool. 5-7Preliminary results suggest that FDT perimetry is a rapid, valid test for glaucomatous field loss. 8-16In a clinical study of glaucoma suspects, Quigley 8 found a sensitivity and specificity of over 90% compared with Humphrey full threshold perimetry. Other investigators have recently corroborated the high specificity but have reported a lower sensitivity. 14-16Although preliminary results are impressive, the optimal interpretation of FDT perimetry data is unclear. Further clinical data are needed before this test can be confidently and accurately applied in clinical practice. Furthermore, there are limited data on the topographical accuracy of FDT perimetry.We conducted a prospective clinic based study comparing FDT perimetry with Humphrey 24-2 (H24-2) perimetry in a consecutive series of patients who were attending our glaucoma clinic. We determined the number of missed points on the FDT perimetry that optimised the sensitivity and specificity of the test in screening mode and determined the ability of FDT perimetry to localise the location and depth of a scotoma. MethodsAll patients involved in the study were attending the glaucoma service at the Stoke Mandeville eye unit, as either a review or a ...

To our knowledge iatrogenic eccentric full thickness macular holes after macular hole surgery have never been reported. We believe that the location of the holes represents the initial site of ILM elevation. These holes are asymptomatic, have not required any treatment and have not caused any complications in up to 6 years of follow-up.

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Aspiration of LECs from the anterior capsule was a safe procedure that reduced capsulorhexis aperture contraction 3 months after cataract surgery.

Macular hole surgery without face-down posturing provides anatomical and functional results comparable to those with prone posturing. Combined phacovitrectomy is not essential to avoid prone posturing.

Crohn disease may be associated with severe PUK leading to corneal perforation. Tectonic corneal grafting combined with treatment of the underlying systemic disease was associated with a favorable outcome.

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