BackgroundHelicobacter pylori (H. pylori) infection affects about 50% of the world population and its association with environmental factors and host properties is involved in gastric carcinogenesis. The study aimed to estimate the prevalence of H. pylori in samples of gastric mucosa biopsies, correlate the presence of the bacteria in the sample with the variables age, sex and origin, to identify the types of lesions found in patients with H. pylori, and to evaluate the association of the lesions with the region of the gastric mucosa.MethodsA cross-sectional, retrospective study was carried out in Aracaju, Sergipe, Brazil, from January 2013 to December 2015. A total of 45,206 gastric mucosal biopsies were obtained from patients submitted to upper gastrointestinal endoscopy. Of the reports evaluated, 12,909 met the inclusion criteria since they presented the patient’s demographic data as well as the histopathological characteristics of gastric mucosal regions and positivity for H. pylori. Data were analyzed by IBM SPSS Statistic 20 and subjected to descriptive analyses (categorical variables) and inferential (Pearson’s Qui-square and linear association tests) and multiple correspondence analyses. Significance level adopted 5%.ResultsOf the total of 12,909 (28.6%) reports evaluated, 67% (8,647) came from urban areas and 64.5% (8,320) were female. The mean age (standard deviation (SD)) was 43 years, ranging from 8 to 100 years, prevailing between 21 and 60 years. Among the types of gastric mucosa analyzed, 95.5% (12,322) were of the antral mucosa. The absence of glandular atrophy, the mild infection intensity for H. pylori, the absence of metaplasia, the presence of foveolar hyperplasia and lymphoid follicles were statistically significant (P < 0.001) in this region. In the fundic region, the evidence of fibrinoleucocytic crust and lymphoid follicles was significant (P < 0.001). There was no evidence of associated ulcerated lesions or significant relationship with intestinal metaplasia in the antral mucosa, whereas the fundic mucosa had a strong association with lymphoid follicles. The prevalence of active H. pylori infection in this study was 30.93%.ConclusionDetection rate of H. pylori and its association with acute and chronic inflammation should be taken into account. The antral region has shown higher incidence and the presence of H. pylori was strongly associated with foveolar hyperplasia and lymphoid follicles.
Backgroud: The exogenous factors such as family dynamics, psychosocial stress, academic hours and lifestyle can alter the quality of sleep and affect the people's physical, occupational, cognitive and social functioning. Objectives: evaluate the epidemiological profile, excessive daytime sleepiness, risk factors and the quality of sleep among university students. Method: Cross-sectional study with 701 Medical and Law students from a private Brazilian Northeastern College. The Sociodemographic profile, Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale questionnaires have been applied. The data were submitted to simple and percentage frequency as well as bivariate and multivariate analysis. Significance level: 5%. Results: The sample was with 659 students, 243(37%) of Medicine and 416(63%) of Law. Age group 18-24 years, predominance of females, age group 18-24 years, female 393 (60%); they self-declared being white 282 (42.7%) and brown 303 (45.9%), said they were single 604(92%) and alcohol consumers more than 60%. Poor sleep quality and sleep disturbance were found in 169(70%) medical students and 221(54%) in law ones, being statistically significant (p <0.001) for the medical students. In this comparison, The Law students presented a higher risk (RR 1.34 (1.15-1.56), p <0.001) for disturbance and poor sleep quality. The risk of excessive daytime sleepiness versus drug use represented 71% (RR 1.71, 95% CI 1.18-2.49) for law students. General concerns, studies, anxiety and insomnia were the most frequent risk factors. Conclusion: Risk factors which are part of Medical and Law students' daily routine affect their sleep quality and increase the risks of excessive daytime sleepiness.
44,7 anos, 13 (61,9%) declararam-se pardos e a maioria possuía algum nível de escolaridade. Não foi detectado tabagistas nem usuários de drogas ilícitas, apenas 3(14,2%) declararam-se usuários de bebidas alcoólica. Quanto ao nível de escolaridade 11 (52,3%) declararam-se colegial completo/ superior incompleto/médio completo. Dos portadores de transtornos dispépticos (n=212), 5(15,6%) pacientes realizaram a endoscopia digestiva alta, e desses, apenas 1(20%) preencheu totalmente os critérios diagnósticos para dispepsia funcional, segundo os critérios de ROMA III. Das comorbidades associadas aos sintomas dispépticos (doenças do coração, respiratórias, sistema digestório, óssea, musculoesquelético, tecido conjuntivo, depressão e ansiedade) a maior prevalência foram as patologias do sistema digestório. Conclusão: diagnosticar dispepsia funcional na pratica clínica torna-se uma condição complexa, na medida que para confirmar o diagnóstico requer que seja preenchido todos os critérios de ROMA III. ABCDExpress 2017;1(2):901Codigo: 61618 Acesso está disponível em www.revistaabcd.com.br e www.sbad2017.com.br Acesso pelo
Introdução: Por orientação sexual depreende-se como padrão de excitação física e emocional de um indivíduo, incluindo fantasias, comportamentos e atividades, e o(s) gênero(s) a quem um indivíduo é física ou sexualmente atraído. Lésbicas, gays, bissexuais e transgêneros (sigla LGBT) fazem parte de uma minoria que sofre muito preconceito e está sob constante estigma, logo, estão envoltos em diversos estressores Objetivo: Estimar a prevalência da população de lésbicas, gays, bissexuais e transexuais (LGBT) no curso de medicina de uma universidade sergipana; identificar possível desconforto quanto à orientação sexual no corpo discente; descobrir indícios de depressão nos participantes da pesquisa segundo a sua orientação sexual; determinar a relação entre desconforto e o relacionamento social acadêmico. Método: Amostra do tipo conveniência com 142 acadêmicos que assinaram o Termo de Consentimento Livre e Esclarecido e responderam quatro questionários: demográfico, Inventário de Depressão de Beck, Escala de Avaliação do Ambiente Acadêmico Frente às Necessidades da População LGBT e a Escala de Percepção de Suporte Social. Resultados: A minoria LGBT apresentou níveis maiores de aceitação e de percepção de suporte social, porém, quanto ao conhecimento de políticas públicas específicas para eles na academia, ambos os grupos demonstraram desconhecimento sobre o tema. Conclusão: Importante discutir sobre questões de gênero e saúde mental, tendo como finalidade buscar suporte psicológico e social aos que estão sofrendo.
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