Sarang semut (Myrmecodia beccarii Hook.f.) is a famous medicinal plant of Papua, which has traditionally potential in treating a wide variety of mild and severe illnesses, such as cancers and tumors, gout, coronary heart disease, hemorrhoids, tuberculosis, migraines, rheumatism, and leukemia. The purposes of this study were to determine the content of the active compound group and the cytotoxic activity of sarang semut plants from Merauke Region. The extraction was done by maceration using 96 % ethanol. The concentration of ethanolic extract were 0, 25, 50, 75, 100 ppm. The results of the study showed that the cytotoxic activity determine using BSLT (Brine Shrimp Lethality Test) method have a high cytotoxic activity with LC50 values of 22.86 ppm and containing the active compound namely flavonoids, tannins and saponins separately. The ethanolic extract of tuber of sarang semut (M. beccarii) has a high cytotoxic activity against larvae of Artemia salina Leach according BSLT method. Key words: Active compound, M. beccarii, cytotoxic activity, Merauke.
Venomous snakebite is an important cause of morbidity and mortality, and is one of the major health problems in many regions of the world. Medicinal Plant which are effectively inhibitor and neutralize the snake venom and it is considered as a valuable source of natural products for development of medicines against venomous snake bite. The biomedical value of these natural inhibitors can lead to the development of new therapeutics for an assortment of diseases as well as contributing to efficient antivenoms for the treatment of ophidic accidents.Key words: pathophysiology, snake bite, envenomation, medicinal plant, therapeutic.
Amphibians and reptiles (herpetofauna groups) produced of many compounds. The herpetofauna and their chemical compounds have been the subject of intense research interest for many years due to their potential in medical application and in lead compound development for new drugs. A number of different types of compounds have been identified from the glandular skin secretions of amphibians and venom or saliva of reptiles. These compounds have been shown to be active against gram-negative and gram-positive bacteria, fungi, enveloped viruses, diabetes mellitus, hypertension and cardiovascular disorder.Key words: Herpetofauna, diabetes mellitus, hypertension, drugs, pathophysiology
Community service with the title: Utilization and how to formulate medicinal plant of African leaf (Vernonia amygdalina Delile) in Keerom Papua, aims to provide the skills of Arsopura Village community in Skamto District of Keerom Regency. The aims to this activities is the use and how to formulate antidiabetic medicinal plants. Diabetes mellitus is a disease caused due to metabolic disorders of the body, where the sugar content in the body can not be catalyzed by the enzyme insulin which was produced the pancreas gland. Herbal antidiabetes formulated from African leaf plants is a traditional knowledge based on local wisdom Kerom community hereditary used to cure diabetes melitus diseases. This activities is an effort to raise the local wisdom about traditional medicine that has been empirically or hereditary has been used as a traditional medicine antidiabetes. Utilization of herbs of traditional medicinal plants need to be socialized by providing skills how to use it and how to formulate to local communities in the Arsopura Village, Keerom regency according to the guidelines regulation of the Supervision of Food and Drug Indonesian Government about the Making of Good Traditional Drugs (CPOTB). According to Institution of Supervision of Food and Drug Indonesian Government that traditional medicine has been used for from generation to generation can be used by the community without having to get permission from The Institution of Supervision of Food and Drug Indonesian Government. Traditional medicine must also have the criteria of safety, quality and efficacy. The purpose of this activities is to provide knowledge on how to utilize and skill how to use herbs of traditional African antidiabetes leaf medicine in Keerom Regency. The method of education used is the lecture or extension method of herbal medicine utilization of traditional antidiabetic medicinal plants, how to use and how to cultivate it. The result data of this activities can be concluded that local people in Arsopura Village, Keerom Regency are very enthusiastic to study the utilization of traditional antidiabetes leaf medicinal plants of Africa and how to mix herbs of traditional antidiabetic medicinal plants and how to cultivate them as Medicinal Plants for family (TOGA). The answer of the question post increasingly and extends to various diseases and herbs that can be used to other disease. Suggestions need assistance in mixing herbs traditional antidiabetes medicinal plants and how to cultivate these plants.Keywords: Herbs, antidiabetes, Vernonia amygdalina, diabetes mellitus, Keerom
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