NSAIDs may reduce breast cancer risk by 20% but the optimal type, dose and duration is still undetermined together with the feasibility of such an intervention in an at risk population. There may be a role for NSAIDs in combination with endocrine therapies as either an adjuvant or palliative treatment for women with established breast cancer.

No abstract

Serum LDH monitoring can be used as a prognostic biomarker in patients of breast cancer. For confirmation of this finding, we require further more studies on larger sample size and long-term follow-up in patients specifically with higher serum LDH levels.

Persistent Müllerian duct syndrome is a rare condition occasionally encountered in men with normal phenotype but with presence of Müllerian duct structures. In India, owing to neglect and lack of facilities, we encounter this condition in adult males. We encountered on the same day in the operation theatre two phenotypic males aged 40 years and 10 months who had inguinal hernia on one side along with contralateral undescended testis. Both patients intraoperatively had uterus with fallopian tubes and underwent subtotal hysterectomy with preservation of vas. Repair of inguinal hernia with fixation of the testis in the scrotum was done. Though rare, every surgeon operating upon inguinal hernia or undescended testes or cryptorchidism needs to know about the presence of the uterus in a phenotypic male patient at any age. High degree of suspicion and awareness is needed to diagnose this condition. Early treatment is needed to maintain fertility and to prevent the occurrence of malignancy in remnant müllerian structures.

This case report throws some light on the way in which the body handles an infected onlay mesh following groin hernia repair. It describes the case of a 73-year-old man who developed this rare complication and demonstrates the mechanism by which this complication occurred.

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Chronic and recurrent abdominal pain is a common problem faced by the medical specialist. It leads to physical and psychological disability in a person. Despite radiological and clinical investigations when diagnosis cannot be ascertained then laparoscopy is one of the modalities that could be of benefit. We aim to evaluate the diagnostic and therapeutic value of laparoscopy in cases with chronic abdominal pain. Sixty-seven patients who attended the outpatient department of MGIMS, Sewagram with chronic and recurrent abdominal pain were included in this prospective study. All patients underwent preoperative workup and were subjected to laparoscopic evaluation. The commonest site of pain was the periumbilical region and nausea was the most common accompanying clinical feature. Adhesions were the most common laparoscopic findings (48.3 %) followed by appendiceal pathology (14.6 %). Abdominal Kochs which is predominant in developing countries was seen in 11.4 % of the cases. Laparoscopy is an effective diagnostic and therapeutic modality in the management of patients with chronic abdominal pain.

No abstract