The aim of this paper is to examine aggressive behaviors among Romanian high school students between 15 and 16 years old, to compare data in two national representative samples and to identify factors associated with physical fighting. This study investigates the association of selected factors (social, school performance and substance use) with physical fighting. A total of 2289 Romanian students were included in the 2007 database and 2770 in the 2011 database. This study revealed that 35.87% of the teenagers have taken part in a physical fight during the previous 12 months, as compared with the European average of 31.5%. Romania has the highest prevalence of violent behavior by participating in a group bruising of an individual in both surveys, 2007 and 2011. A logistic regression analysis performed for the 2011 study revealed the following factors associated with physical fighting: binge drinking during the previous 30 days, male gender, serious problems with friends, parent(s) who do not know where and with whom the adolescents spend their evenings, poor parental caring, low school grades, and high truancy. A decrease in almost all aggressive behaviors was noticed in 2011, compared to 2007. These findings may be useful to support and guide policy makers regarding improvement and implementation of strategies to further prevent aggressive behaviors in teenagers.
Background and Objectives: Responding to the need for additional biomarkers for the diagnosis of prostate cancer (PCa), mounting studies show that microRNAs (miRNAs/miRs) possess great potential as future promising diagnostic tools. However, the usefulness of these miRNAs is still highly debated, as the degree of inconsistency between study designs and results is still elevated. Herein, we present a meta-analysis evaluating the diagnostic value and accuracy of circulating miR-375, as it is one of the most studied types of miRs in PCa. Materials and Methods: The diagnostic accuracy of miR-375 was evaluated using the QUADAS-2 tool, analyzing different statistical parameters. The seven studies (from six articles) that matched our selection included 422 PCa patients and 212 controls (70 healthy volunteers + 142 with benign prostate diseases). Results and Conclusion: We obtained a p-value of 0.76 for sensitivity, 0.83 for specificity, 16 for DOR, 4.6 for LR+, 0.29 for LR−, and 0.87 for AUC (95% CI 0.83–0.89). Our results confirm that miRNA-375 has high diagnostic potential for PCa, suggesting its usefulness as a powerful biomarker. More comprehensive studies are warranted to better assess its true value as a diagnostic biomarker for this urologic disease.
Medical professionals require adequate abilities to identify others’ emotions and express personal emotions. We aimed to determine the validity and reliability of an empathy measuring tool in medical students for this study. We employed Spreng’s Toronto Empathy Questionnaire (TEQ) as a starting point for this validation. The process was performed in several steps, including an English-Romanian-English translation and a focus group meeting to establish each question’s degree of understandability and usability, with minor improvements of wording in each step. We checked internal and external consistency in a pilot group (n = 67). For construct and convergent validity, we used a sample of 649 students. The overall internal and external reliability performed well, with Cronbach’s alpha = 0.727 and respective ICC = 0.776. The principal component analysis resulted in 3 components: prosocial helping behavior, inappropriate sensitivity, dismissive attitude. Component 1 includes positively worded questions, and components 2 and 3 include negatively worded questions. Women had significantly higher scores than men in convergent validity, but we did not highlight any differences for other demographic factors. The Romanian version of the TEQ is a reliable and valid tool to measure empathy among undergraduate medical students that may be further used in subsequent research.
Background: Coronary heart disease is a public health problem, and the leading cause of premature death in Europe and worldwide. There is epidemiological evidence that the control of cardiovascular risk factors following myocardial revascularization remains suboptimal.
Background and aims: C-reactive protein (CRP) is an inflammatory biomarker that may be associated with diabetic retinopathy (DR). The body mass index (BMI) is
The Hodgkin lymphoma treatment is adapted to the disease type, disease stage and to an evaluation of the risk. The treatment is focused on the adjustment of the therapy to each patient depending on the age, toxicity risk on short and long term and the relapse risk. The study proposes the evaluation of the response to the treatment further to the administration of different therapeutic regimens as well as the correlation with the negative diagnosis factors of Hodgkin lymphoma. This is a retrospective study on 71 patients diagnosed with Hodgkin lymphoma in the Hematology Department of Timisoara between January 2014 and December 2017. The data obtained have been collected from a database and processed with the SPSS 20.0. software . In our study there were included 71 patients diagnosed with Hodgkin lymphoma with a medium age of 42.12�16.45 years old. By the time of the diagnosis, the patients showed the following hematological, biochemical and immunological parameters. The response to treatment is influenced by the presence of the negative prognosis factors : the age of �40 years old, extralymphatic infiltration, VSH ] 50mm/h , presence of general B signs, more than 3 lymph node sites affected, bulky disease and Ann-Arbor III and IV stages. The treatment of Hodgkin lymphoma is guided by the traditional clinic prognostic factors and by the laboratory which often represent a substitute marker for the biological characteristics which many times are not included in the standard evaluation.
Many prognostic factors for HL have been proposed in the past and some of these were included in several prognostic scores. Tumor stage and spread, age, gender and various biological parameters are considered to have an effect on disease evolution, with the prognostic scores stratifying patients into risk groups and guiding the course of treatment. In the present study we have enrolled 54 patients with Hodgkin�s lymphoma admitted in the Hematology Department within the City Emergency Clinical Hospital Timisoara over a 4-year period. We aimed to see if a statistically significant correlation can be made between hemoglobin, white blood cell, lymphocyte, eosinophil, monocyte and platelet levels at the time of diagnosis on the one hand, and response to treatment and patients� survival, on the other hand. Patients� response to treatment was evaluated according to Cheson criteria, with best response to the combination of ABVD(doxorubicin C27H29NO11, bleomycin C55H84N17O21S3, vinblastine C46H58N4O9, dacarbazine C6H10N6O) and radiation therapy. Response to treatment was also influenced by eosinophil levels at diagnosis and this has effects on survival. Finally, lymphocyte and platelet levels at diagnosis correlated with survival times in our study group. Therefore, eosinophil, lymphocyte and platelet levels at diagnosis could be considered as prognostic factors for HL, although further studies are needed to validate our findings.
Introduction The current period is marked by several negative aspects of the COVID 19 pandemic, which have led to a series of emotional and cognitive changes that affect our functioning. The ability to “read” the minds of others is the key aspect of social behavior, helping us understand our context. Objectives To identify the level of emotion recognition in Medicine students during the Covid 19 pandemic. Methods Throughout 2021, we evaluated 649 Romanian General Medicine students in years 4, 5 and 6, by using a Google Play application (android and iOS). We analyzed socio-demographic parameters and the affective component of Theory of Mind (The Reading the Mind in the Eyes Test). The mean scores between groups were compared with the Student’s t and the ANOVA tests. Results The mean score was 25.83 ± 3.36 (min 11, max 33) out of a possible maximum of 36. We noted that women have a higher capacity for recognizing emotions than men (26.04 ± 3.22 vs. 25.01 ± 3.78, P = 0.0016) without differences in terms of the study year. Also, women showed a greater ability to recognize negative emotions compared to men (16.57 ± 2.44 vs. 15.49 ± 2.75, P <0.001). No statistically significant differences were found between the two genders in terms of positive emotions’ recognition. Conclusions The ability to recognize emotions seems to be more developed in women, especially when it entails recognizing negative emotions. Theory of Mind abilities are important for empathy and the therapeutic relationship required in Medicine. Disclosure No significant relationships.
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