<p>Kematian akibat Covid-19 menurut <em>Centers for Disease Control and Prevention</em> di Amerika Serikat terjadi pada pasien rentan dan memiliki riwayat komorbid penyakit seperti hipertensi. Virus SARS Cov-19 masuk kedalam sel manusia dan menginfeksi melalui ikatan dengan reseptor <em>Angitensin Converting Enzym 2</em> (ACE 2). Terapi farmakologi pada penanganan Covid-19 dengan riwayat komorbid hipertensi dalam tahap pengujian secara klinis masih perlu dilakukan monitoring pengobatan yang tepat dan rasional sehingga perlu pengkajian farmakoterapi berdasarkan derajat keparahan penyakit. Penelitian ini bertujuan memahami faktor yang mempengaruhi derajat keparahan penyakit dan karakteristik terapi Covid-19 pada pasien rawat inap komorbid hipertensi. Penelitian ini menggunakan desain penelitian <em>cohort retrospective</em><em>. </em>Pengambilan data di RSJPD Harapan menggunakan rekam medis pasien rawat inap dengan pasien Covid-19 pada komorbid hipertensi pada periode November 2020 sampai April 2021. Teknik pengambilan sampel menggunakan <em>consequtive sampling</em> dan Analisis statistik <em>Chi square</em>. Hasil penelitian menunjukan,dari 80 pasien, subjek penelitian laki-laki sebanyak 45 pasien (56,31%), usia produktif 45 pasien (56,30%). Kesesuaian peresepan dosis dan frekuensi terapi Covid-19sebesar 99,03%. Hasil analisis bivariat menunjukan adanya perbedaan bermakna pada pemberian terapi suportif Covid-19 (p=0,034), saturasi oksigen (p=0,024) serta lama perawatan pasien (p=0,008) terhadap derajat keparahan penyakit. Adapun hasil terapi Covid-19 memiliki perbedaan bermakna terhadap derajat keparahan, terdapat pada terapi levofloxacin (p=0,034);osetalmivir (p=0,030); favipiravir (p=0,027); remdesivir (p=0,009) dan spironolakton (p=0,034).</p>
Sebagian besar kalangan ibu rumah tangga masih minim mengenal beberapa jenis bumbu dapur sebagai obat tradisional yang memiliki kandungan zat aktif bersifat imunostimulan. Penduduk Pademangan Barat salah satu wilayah yang mempunyai kasus terbanyak COVID-19 di wilayah DKI Jakarta serta nilai kesehatan relatif rendah dibanding kelurahan lain. Kegiatan pengabdian masyarakat bertujuan memberikan pelatihan bumbu dapur sebagai obat tradisional dan menjadi alternatif minuman berbasis herbal instan dan sehat pada masa pandemi COVID-19. Metode yang digunakan adalah metode penyuluhan. Kegiatan pengabdian masyarakat oleh dosen dan mahasiswa Jurusan Farmasi Poltekkes Kemenkes Jakarta 2 meliputi pelatihan pengenalan bumbu dapur sebagai minuman herbal serta pengolahan serbuk jahe dan temulawak berkarbonasi sebagai alternatif minuman kesehatan. Hasil kegiatan dan pelatihan ini memberikan pengetahuan dan keterampilan mengenai pembuatan serbuk instan jahe dan temulawak berkarbonasi kepada mitra kelompok kader PKK, pengelola RPTRA serta warga kelurahan Pademangan Barat. Kegiatan pengadian masyarakat diharapkan meningkatkan derajat kesehatan dan perekonomian masyarakat di Kelurahan Pademangan Barat Jakarta Utara
The household drug management is common practice worldwide especially Ethical drugs and OTC Drugs that indicated are acute and chronic condition. The beside higher costs, accumulation medicines at home can be attributed to the lack of knowledge and behavior in patient, patient's family and environmental. Negative relationships in household drug management more likely risk for elderly people have many illnesses and polypharmacy, drug interactions and adverse drug reactions. The objective of this study to analyze the factors Associated to behavior Dagusibu drug management in Community Jakarta Pusat With Home Pharmacy Care. This research used observational research by using cross-sectional design. this research type probability sampling with technique is cluster random sampling. The data analysis used bivariate analysis , especially chisquare test. The result of multivariate analysis showed the variable were significantly related to behavior dagusibu drug management, namely variables were medicine dispossal box (p=0.019;OR 3.009); medicine safety box (p=0.025;OR 2.974) and influence efect of family support (p=0.001;OR=5.092).
Uncontrolled antibiotics use can induce antibiotics resistance cases. The community believe that antibiotics can cure all disease. Because of that Pharmacist is needed home pharmacy care related by antibiotics use knowledge to justify people's misconceptions. The main purpose of this research to analysis relationship between knowledge of behavior using antibiotics in Kelurahan Petukangan Utara with home pharmacy care. This research is non-experimental with a cross sectional study design. The sample used in this research was the community of Kelurahan Petukangan Utara with cluster random sampling metode is 101 responden by questionnaires. The data analysis used chi-square statistic test. The results showed that there were categories of antibiotic knowledge (55.4%) and antibiotic Behavior (53.5%). There is a significant relationship between knowledge with community behavior antibiotics use with p-value=0.015; OR: 4.979 in Kelurahan Petukangan Utara
Severe acute respiratory syndrome coronavirus-2 (SARS-nCoV-2) the cause of Coronavirus Disease 2019 (COVID-19) was first discovered in Wuhan on December 2019, has spread throughout the world. Each country tries to develop treatment protocol guidelines following the latest research developments to increase the cure rate due to the absence of standard guidelines.The purpose of this research is to knowing the profile of prescribing COVID-19 drug therapy in inpatients at jakarta haji hospital the period September 2020-February 2021. This research is non-experimental with quantitative descriptive study design was taken retrospectively using secondary data in the form of prescription data history of COVID-19 patient visits recorded on the system with sampling techniques that is total sampling. The results showed that in total 387 COVID-19 patients the most were 46-65 years oldwith 198 patients and the mostly malewith 212 patients. The longest duration of treatment was 3-10 days as many as 246 patients and the highest degree of disease was mild to moderate as many as 363 patients The most widely prescribed drugs were Paracetamol (84.37%), Dexamethasone (78.4%), Osetalmivir (74.1%), Heparin (67.81%), Alprazolam (60.27%), Acetylsitein (58 ,12%), Insulin (54.93%), CTM (53.13%), Amlodipine 50.43%, Vitamin C (48.04%), Levofloxacin (35.48%), and Omeprazole (31.98 %). COVID-19 patients at the Jakarta Haji Hospital receive the main therapies, namely vitamins, antibiotics, antivirals, respiratory drugs, gastrointestinal drugs. The suitability of prescribing drug therapy classes based on the guidelines for the management of COVID-19 is 83% and those that are not in accordance with the guidelines are 27%.
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