Purpose:The aim was to evaluate the knowledge of the students of dental students regarding patients care towards HIV positive individuals. Methods:Two hundred and eighty-three dental students (pre-clinical, n = 45; clinical, n = 238) answered an electronic questionnaire, approaching biosafety procedures, oral manifestations of AIDS and knowledge of HIV infection. Data were present as an average from findings from students of nine different semesters, grouping them by pre-clinical (1-4) and clinical (5-9) semesters, from two different university campuses.Furthermore, data were analysed using the t test and chi-square test.