Background: Musculoskeletal disorders are very common among the diabetic patients and frozen shoulder is one of the disabling conditions. The present study was conducted to compare the serum triglyceride level among the patients of type 2 diabetic presented with and without frozen shoulder. Methodology: This case control study was conducted from January 2008 to December 2009, in the department of Physical Medicine and Rehabilitation, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka with an aim to compare the serum triglyceride level among diabetic patients presented with, and without frozen shoulder. Thirty types 2 diabetic patients with frozen shoulder were selected as cases and similar number well matched type 2 diabetic patients without frozen shoulder were selected as control. Results: We prospectively studied 30 diabetes mellitus (type 2) patients with the diagnosis of frozen shoulder. The blood sugar both fasting and 2 hours after breakfast, HbA1c and serum triglyceride levels were measured in all patients and compared with those in 30 diabetic patients without frozen shoulder. The blood sugar, fasting and 2 hours after breakfast, HbA1C and serum triglyceride levels were significantly elevated in the frozen-shoulder group (fasting blood sugar p = 0.012; blood sugar 2 hours after breakfast p<0.01; HbA 1C p<0.05; and triglyceride p < 0.001).Conclusion: Diabetic type 2 patients presented with frozen shoulder had higher serum triglyceride level compare to the diabetic type 2 patients without frozen shoulder.
IntroductionPainful diabetic polyneuropathy is a common manifestation of diabetes mellitus 1 . Painful diabetic polyneuropathy significantly affect on the quality of life, sleep, mood, mobility, ability to motor activities and social behaviors of patients 2 . High prevalence of diabetes and consequently painful neuropathy limits the daily activities of the patients 3 .Diabetic neuropathy is one of the most underestimated, very common and early among the complications of diabetes mellitus (DM) 4 . The most common type of neuropathy in DM is diabetic peripheral neuropathy (DPN), with up to 50% of patients experiencing some degree of painful symptoms and 10% to 20% having symptoms severe enough to warrant treatment 5 . A classic population-based study found some degree of neuropathy in 66.0% of patients with DM. Among those 54.0% with type 1 and 45.0% with type 2 DM had DPN. This study has also shown that 15% of DPN in type 1 and 13% in type 2 DM are symptomatic 6 . Prevalence of neuropathic symptoms increases with the duration of diabetes and quality of glycemic control 7 . Although 7.5% diabetics, at the time of diagnosis, can have neuropathy, the incidence increases to about 50% after 20 to 25 years of diabetic life 3 . Up to 25% of individuals with Abstract Introduction: Diabetic neuropathy is one of the early complications of diabetes mellitus patients which is very difficult to face in the daily living activities. The purpose of the present study was to see the demographic characteristics of diabetic neuropathy patients. Metarials & Methods: This descriptive type of cross-sectional study was conducted in the Department of Neurology including Neuropathy Clinic and in collaboration with department of Endocrinology at Banghabandhu Sheikh Mujib Medical University, Dhaka from January 2012 to December 2013 for a period of two (2) years. Adult diabetic patients presented with neuropathic pain with symmetrical involvement of distal limbs from indoor and outpatient department of Neurology including Neuropathy clinic as well as indoor and outpatient department of Endocrinology, BSMMU were enrolled in the study population. Data was collected by face to face interview. Information was collected by taking medical history and clinical examinations and subsequent laboratory investigations. Results: A total number of 102 cases were recruited for this study who were clinically diagnosed as painful diabetic polyneuropathy. Female was predominant than male 55(53.9%) cases and 47(46.1%) cases respectively. The male and female ratio was 1:1.2. Majority were in the age group of more than 55 years which was 55(53.9%) cases. The mean age with SD of the study population was 52.79±9.42 years. Among 102 patients type II DM was predominate than type I patients which were 95(92.2%) cases and 8(7.8%) cases respectively. The mean duration of DM with SD was 6.51±3.6 years. However the mean duration of neuropathic pain was 1.68±1.155 years. Conclusion: In conclusion majority of the diabetic neuropathy patients are female suffering from type I...
Background: Depression is a non-motor symptom in Parkinsons disease (PD) as well as elderly population due to testosterone deficiency (TD). Because of similarity between depression in PD and for testosterone deficiency, clinician may fail to recognize and treat TD in patients with PD. Objectives: Our aim was to find out the association between serum total testosterone level and depression in men with Parkinson disease. Methods:This was a case control study carried out in the OPD of department of Neurology, Department of Psychiatry and Department of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU) on total of 64 subjects where 34 were cases and 30 were controls age ranging from 40 to 85 years of age. Results: This analysis showed serum testosterone levels were significantly low in PD patients with depression compared to controls ( 4.90±1.86 ng/ml in cases and 6.66±1.18 ng/ml in control group with Odds ratio is 2.071; 95% CI 1.587-2.704). Significantly (P <0.05) low levels of serum testosterone were noted in case suffering from depression more than one year (4.56±1.82 ng/ml vs 6.18±1.50 ng/ml). Serum testosterone level was significantly (<0.001) low in stage III PD patients with depression compared to control (4.96±1.41 ng/ml vs 7.30±1.23 ng/ml). Conclusion: Low serum testosterone level is an important factor causing depression in PD patients. Also progression of PD and duration. Bangladesh Journal of Neuroscience 2011; Vol. 27 (2) : 57-63 DOI: http://dx.doi.org/10.3329/bjn.v27i2.17541
Background: Alzheimer’s disease is the most common cause of dementia. Uric acid is the end product of purine metabolism in humans and acts as a natural antioxidant, accounting up to 60% of the free radical scavenging activity in human blood to prevent free radicals induced oxidative cell injury. This study aimed to explore the association between serum uric acid level and cognitive impairment of Alzheimer’s disease patients compared to those of the non-demented age and sex matched controls. Methods: This case control study was carried out in the department of neurology, BSMMU, Dhaka. Total 116 patients were enrolled as study population after satisfying inclusion and exclusion criteria. Among them, 58 were grouped as case and rest 58 were control. All blood samples for serum uric acid were measured in the Biochemistry lab, Department of Biochemistry, BSMMU, Dhaka. Results: A signiûcant reduction of serum uric acid levels in the AD group was found compared to those of the control group (4.35±1.59 Vs 6.89±1.68) which was statistically significant (p<0.001). We also found a positive correlation between serum uric acid levels with severity of Alzheimer’s disease (rp = 0.633, P<0.001). Among demographic variables educational qualification was statistically significant (p=0.006) in AD patients. Conclusion: This study showed that oxidative injuries have an important role in the pathogenesis of AD. Higher levels of uric acid are associated with a decreased risk of dementia and better cognitive function later in life. Bangladesh Journal of Neuroscience 2017; Vol. 33 (2): 83-88
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