Introduction Because of the inadequate level of public awareness of the disease, the incidence of stroke has been sharply rising. Eventually, due to the prehospital delay, many stroke cases could not be eligible for thrombolysis thereby poor rehabilitative outcome has been tremendously increased. Thus, this study aimed to review the level of knowledge, prevention practice, and associated factors of stroke among hypertensive and diabetic patients. Methods A systematic review of primarily published articles (2010–2020) related to knowledge and prevention practices of stroke was performed by searching online electronic databases like PubMed, Google Scholar, Refseek, Science direct, ResearchGate, and manual Google search by using the keywords and MeSH terms. Studies conducted on knowledge and prevention practices amongst hypertensive and/or diabetic patients were included. Results Out of 531 searched studies, 42 articles were identified to be reviewed. The reported overall knowledge of stroke was ranging from 4.4% to 79%. Knowledge to the signs/symptoms of stroke was 23.6% to 87%. However, 15% to 77% of subjects were also reported that they did not know any sign of stroke. The range of risk factor knowledge was 10.5% to 86.6%. The reported level of stroke prevention practice was 2.4% to 72% but physical activity and weight reduction practice were relatively low. Inadequate level of knowledge and prevention practice of stroke was related to elderly, female gender, uneducated, unmarried, rural residents, economically low, comorbidity and unemployed individuals. Conclusion The current finding revealed that the level of knowledge and prevention practice of stroke was inadequate. Hence, the finding highlights health educational programs should be planned as an important avenue to enhance stroke awareness among the high-risk populations.

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Background: Because of poor health care service delivery and a low level of public awareness of the disease the incidence and disability rate of stroke has been increased. The study aimed to assess the knowledge, prevention practice, and associated socio-demographic factors towards stroke among hypertensive and diabetic patients. Method: Cross-sectional based study design was applied on hypertensive and diabetic patients after they were selected with a simple random sampling technique. The data were collected with a structured intervieweradministered questionnaire. Result: All the computed 382 respondents responded with a response rate of 100%. Among the participants 52.36% were males. The finding showed that the respondents had 36.65% and 42.67% good knowledge and prevention practice of stroke respectively. The associated demographic factors with good knowledge of stroke were urban residency [AOR, (95% CI), 4.54 (2.23-9.25)], Age <50 years [AOR, 95% CI; 1.80 (1.06-3.05)], educational status [AOR, 95% CI; 2.78 (1.45-5.31)], monthly income [AOR.95% CI;] and >5 years' duration of the disease [AOR, 95% CI;]. Similarly, urban residency [AOR, (95% CI); 1.91 (1.06-3.43)], being educated [AOR, 95% CI; 2.98 (1.67-5.31) monthly income [AOR, 95% CI; 2 (1.20-3.32)] and medical condition become hypertension (HTN) with Diabetes mellitus (DM) [AOR, 95% CI;] were strongly associated factors with good prevention practice of stroke. However, the occupational status being Farmer [AOR, 95% CI; 0.31 (0.107-0.91)] was preventive against good prevention practice of stroke. Conclusion:The study showed that the respondent's level of knowledge and prevention practice towards stroke was limited.