In this era of great health challenges, organ donation may be the only intervention to failing and failed organs. Organ donation is willingly accepting to donate an organ or part of an organ to someone with a failing organ or failed organ. There are very few voluntary donations. Cadavers a major tool in the study of anatomy is gotten through unclaimed bodies, corpse from condemned criminals and donation of corpse for teaching and research. This cross sectional survey includes 707 students, 390 dissecting students and 317 non dissecting students from the Faculty of Basic Medical Sciences, Delta State University Abraka. Structured questionnaires were administered to the student and date analysed. This was done to know the perception of student to organ and corpse donation and to assess if dissection affects the willingness to donate one’s organ or corpse for research. Result generally showed a negative attitude to organ and corpse donation. Only 5.9% considered donating their organs and 4.1% considered donating their corpse for research. The poor attitude towards organ and body donation may be attributed to people not wanting their body to be disrespected (30%), fear of the effect of donation (23%), religious beliefs (10%), and traditional beliefs (6%). Surprisingly lack of awareness to donation of organs and corpse accounted for a few percentages.
There has been a drastic widespread use and abuse of dichlorvos (DDVP) with increasing accidental and intentional exposure. Hence, the need for a local therapeutic remedy before medical intervention. This study aimed to show the ameliorative properties of Mimosa pudica (MP) on DDVP induced neurotoxicity. 50 adult BALB/c mice were randomly divided into 5 groups of 10 mice each. Mice were given normal feed or poisoned feed (2.5% of dichlorvos in feed) with or without MP extract treatment. The exposure lasted for 28 days and all administration was done orally. At the end of exposure, mice were euthanized using chloroform and perfused transcardially using 1X PBS followed by 10% formal saline for animals designated for histochemical evaluations. Exposure to DDVP reduces granular cell layer thickness, altered Nissl substance distribution, elevates expression of GFAP and CD68 compared to control, co-administration with MP extract did not considerably reversed these effects unlike DDVP+MP that showed similar observation to control mice. GR was significantly high in all groups than the control except DDVP+MP and the level of SOD was significantly reduced in DDVP mice compared to other groups. DDVP induced hippocampal alterations accompanied by oxidative stress reversed by subsequent treatment with MP extract.
The morphometric parameters of the maxillary sinus are important in the forensic identification of unknown human skulls. This study aimed at determining the accuracy of using the dimensions of the maxillary sinus in sex determination. Skull Computed Tomography images of 292 adult patients, stored in the Radiology Department of a teaching hospital in Nigeria were retrospectively used to measure the dimensions of the maxillary sinus after obtaining the institution's approval. Using the Statistical Package for Social Sciences Version 23, the side and gender comparisons were evaluated using student's t-test while the correlation between the metric parameters was determined using Pearson's test. P-value was considered significant at <0.05. Discriminant function analysis was used to evaluate the accuracy of using the dimensions for sex prediction. The dimensions of the maxillary sinus were significantly larger in males than in females (p<0.05) but lacked significant association with age (p>0.05). The left maxillary sinus height was the best sex discriminating variable (238,81.5%). The accuracy of correct sex prediction increased when all the dimensions of the right (240,82.2%), left (243,83.2%) or both maxillary sinuses (258,88.4%) were used. In conclusion, the MS dimensions may be used for sex determination with acceptable accuracy in the studied population.
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