Introduction: Pre-Eclampsia (PE) is the common multisystem disorder which complicates the pregnancies 3-8% and a major cause of morbidity and mortality throughout the world. Aim: To determine the correlation of placental growth factor with PE in mid trimester of pregnancy at Liaquat University of Medical and Health Sciences Jamshoro. Materials and Methods: This Case-Control study was performed at Pathology Department with Department of Obstetrics and Gynaecology, Liaquat University of Medical and Health Sciences (LUMHS) Jamshoro/Hyderabad, during 12 months, from 6th February, 2017 to 5th February 2018. Pregnant women with mid trimester were enrolled in the study. Group A included females with PE, while Group B were normotensive females of same gestation. Their blood sample were collected and stored at -80°. Level of placental growth factor was measured on Elecsys system. Data was analysed via Statistical Package for the Social Sciences (SPSS) version 20. Results: Total 384 PE females were selected and 50 females without hypertension were studied as control. Mean age of patients was 27.46±3.91 years. No significant variance was seen between mean of gestational age of patients and normal pregnant females; p-value 0.346. Mean of placental growth factor was insignificantly decreased 35.21±31.68 pg/mL among patients in contrast to normal women as 47.23±56.13 pg/mL, p=0.081. A negative correlation was found between blood pressure and placental growth factor, r-values -0.004 and -0.001, respectively. Conclusion: It was concluded that serum placental growth factor was the poor marker for PE, as it showed weak negative correlation with PE.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.