Xanthogranulomatous inflammation, which is known to occur in several viscera, is rarely found to affect the pancreas. We report a case of xanthogranulomatous pancreatitis (XGP) occurring in a 60-year-old man who presented with epigastric pain and vomiting. Physical examination did not reveal any abnormality. Contrast-enhanced CT of the abdomen revealed an ill-defined, heterogeneous mass lesion in the uncinate process of the pancreas, suggestive of malignancy. Whipple's pancreaticoduodenectomy was performed and the final pathological diagnosis was XGP. The patient's postoperative course was uneventful. When a pancreatic mass does not show clinicoradiological features typical of common pancreatic neoplasms, XGP should be considered for a differential diagnosis and duodenum preserving surgery can be considered.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.