A case control study was conducted on 49 subjects 29 of them with chronic renal disease and 20 subjects as control with age range between (45-75) years were investigated to determine the correlation of salivary and serum cystatin, urea and creatinine to assess their significance in the diagnoses of patients with chronic renal disease. The results indicated that the level of salivary cystatin was significantly (P ≤ 0.05) elevated in chronic renal disease (292.517±37.19 ng/ml) as compared to control (144.45±22.963 ng/ml). The level of serum cystatin was significantly (P ≤ 0.05) elevated in chronic renal disease (498.414±59.091 ng/ml) as compared to control (391.60±49.488ng/ml). The level of serum creatinine was significantly (P ≤ 0.05) elevated in chronic renal disease (4.369±0.799 mg/dl) as compared to control (1.007± 0.180 mg/dl). The level of urea was significantly (P ≤ 0.05) elevated in chronic renal disease (56.138±5.908 mg/dl) as compared to control (31.80 ± 5.176 mg/dl). From all the above results, we can conclude that salivary cystatin can be considered as a better biochemical marker for renal function compared to serum cystatin in chronic renal disease.
The current study included collection of 90 serum samples to assess the relationship between the level of vitamin D3 and some biochemical variables in women with polycystic ovarian syndrome. The samples were collected from external laboratories in Salah al-Din Governorate for the period from 10/29/2021 to 12/25/2021. 60 samples were taken for women with PCOS, and 30 samples were taken from the control group, their ages ranged between (18-40) years for healthy women and patients. Vitamin D3 level and some hormones concentrations (luteinizing hormone, follicle-stimulating hormone, and testosterone) were estimated in the blood serum of the study groups. The results of the current study showed that the level of vitamin D3 decreased significantly (P≤0.05) in women with PCOS compared to healthy women as a control group, the results showed a significant increase (P≤0.05) in the level of studding hormones (luteinizing hormone, follicle-stimulating hormone, and testosterone) in women with PCOS compared to healthy women as a control group.
تضمنت الدراسة 50 مريضا (18 اناثاً) و (32 ذكوراً) مصابين باحتشاء العضلة القلبية وتتراوح اعمارهم ما بين (40-73) سنة، تم اختيارهم عن طريق تشخيص حالاتهم المرضية في مستشفى سامراء، للفترة من 1/9/2019 والى 9/6/2020 , وتم مقارنتها مع مجموعة السيطرة التي تضمنت 25 عينة من الاشخاص الاصحاء. تم قياس مستوى الفايبرونكتين في الدم واللعاب، ومستويات الدهون في المصل والمتمثلة بالكولسترول الكلي والدهون الثلاثية والبروتينات الدهنية واطئة الكثافة. وأظهرت النتائج ارتفاعا معنويا (05p ≤ 0.) في مستوى الفايبرونكتين في مصل المرضى 5.771±1.461)) نانو غرام /مل مقارنة بمجموعة السيطرة (0.374±0.089) نانو غرام / سم 3، وانخفض تركيز فايبرونكتين اللعاب معنويا (05 .0p ≤ ) في المرضى (0.424±0.110) نانو غرام / مل مقارنة بالأصحاء (9.775±2.808) نانو غرام / مل .و أظهرت النتائج ارتفاعا معنويا (05 p ≤ 0.) في تراكيز كل من (الكولسترول، TG، (LDL-Ch في المرضى ((230.62±34.989، ((217.60±39.894، (152.34±35.319) ملغم/100مل مقارنــة بمجمــوعة السيطـــــــرة (169.20±21.136) ،(32.058± 132.92)، (69.04±10.510) ملغم/ 100مل على التوالي و اظهرت النتائج وجود علاقة أيجابية بين مستوى الفايبرونكتين في المصل واللعاب، وبين مستوى الفايبرونكتين والكولسترول، وعلاقة ارتباط معنوية بين فايبرونكتين المصل وTG ,LDL , بالنسبة للأشخاص الاصحاء.
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